Planning Study Comparison of Real-Time Target Tracking and Four-Dimensional Inverse Planning for Managing Patient Respiratory Motion

Peng, Zhang; Hugo, Geoffrey D

doi:10.1016/j.ijrobp.2008.07.025

Title: Planning Study Comparison of Real-Time Target Tracking and Four-Dimensional Inverse Planning for Managing Patient Respiratory Motion

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Abstract

Purpose: Real-time target tracking (RT-TT) and four-dimensional inverse planning (4D-IP) are two potential methods to manage respiratory target motion. In this study, we evaluated each method using the cumulative dose-volume criteria in lung cancer radiotherapy. Methods and Materials: Respiration-correlated computed tomography scans were acquired for 4 patients. Deformable image registration was applied to generate a displacement mapping for each phase image of the respiration-correlated computed tomography images. First, the dose distribution for the organs of interest obtained from an idealized RT-TT technique was evaluated, assuming perfect knowledge of organ motion and beam tracking. Inverse planning was performed on each phase image separately. The treatment dose to the organs of interest was then accumulated from the optimized plans. Second, 4D-IP was performed using the probability density function of respiratory motion. The beam arrangement, prescription dose, and objectives were consistent in both planning methods. The dose-volume and equivalent uniform dose in the target volume, lung, heart, and spinal cord were used for the evaluation. Results: The cumulative dose in the target was similar for both techniques. The equivalent uniform dose of the lung, heart, and spinal cord was 4.6 {+-} 2.2, 11 {+-} 4.4, and 11 {+-} 6.6 Gy for RT-TT withmore »« less

Authors:

Peng, Zhang; Hugo, Geoffrey D ^[1]

Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI (United States)

Publication Date:: Sat Nov 15 00:00:00 EST 2008

OSTI Identifier:: 21172478

Resource Type:: Journal Article

Journal Name:: International Journal of Radiation Oncology, Biology and Physics

Additional Journal Information:: Journal Volume: 72; Journal Issue: 4; Other Information: DOI: 10.1016/j.ijrobp.2008.07.025; PII: S0360-3016(08)03111-8; Copyright (c) 2008 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0360-3016

Country of Publication:: United States

Language:: English

Subject:: 62 RADIOLOGY AND NUCLEAR MEDICINE; CARCINOMAS; COMPUTERIZED TOMOGRAPHY; HEART; IMAGES; LUNGS; PATIENTS; PLANNING; RADIATION DOSE DISTRIBUTIONS; RADIATION DOSES; RADIOTHERAPY; RESPIRATION; SPINAL CORD

Citation Formats


                    Peng, Zhang, Hugo, Geoffrey D, and Yan Di. Planning Study Comparison of Real-Time Target Tracking and Four-Dimensional Inverse Planning for Managing Patient Respiratory Motion.  United States: N. p., 2008. 
        Web.  doi:10.1016/j.ijrobp.2008.07.025.

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                    Peng, Zhang, Hugo, Geoffrey D, & Yan Di. Planning Study Comparison of Real-Time Target Tracking and Four-Dimensional Inverse Planning for Managing Patient Respiratory Motion.  United States.  https://doi.org/10.1016/j.ijrobp.2008.07.025

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                    Peng, Zhang, Hugo, Geoffrey D, and Yan Di. 2008.  
        "Planning Study Comparison of Real-Time Target Tracking and Four-Dimensional Inverse Planning for Managing Patient Respiratory Motion".  United States.  https://doi.org/10.1016/j.ijrobp.2008.07.025.

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@article{osti_21172478,

  title        = {Planning Study Comparison of Real-Time Target Tracking and Four-Dimensional Inverse Planning for Managing Patient Respiratory Motion},

  author       = {Peng, Zhang and Hugo, Geoffrey D and Yan Di},

  abstractNote = {Purpose: Real-time target tracking (RT-TT) and four-dimensional inverse planning (4D-IP) are two potential methods to manage respiratory target motion. In this study, we evaluated each method using the cumulative dose-volume criteria in lung cancer radiotherapy. Methods and Materials: Respiration-correlated computed tomography scans were acquired for 4 patients. Deformable image registration was applied to generate a displacement mapping for each phase image of the respiration-correlated computed tomography images. First, the dose distribution for the organs of interest obtained from an idealized RT-TT technique was evaluated, assuming perfect knowledge of organ motion and beam tracking. Inverse planning was performed on each phase image separately. The treatment dose to the organs of interest was then accumulated from the optimized plans. Second, 4D-IP was performed using the probability density function of respiratory motion. The beam arrangement, prescription dose, and objectives were consistent in both planning methods. The dose-volume and equivalent uniform dose in the target volume, lung, heart, and spinal cord were used for the evaluation. Results: The cumulative dose in the target was similar for both techniques. The equivalent uniform dose of the lung, heart, and spinal cord was 4.6 {+-} 2.2, 11 {+-} 4.4, and 11 {+-} 6.6 Gy for RT-TT with a 0-mm target margin, 5.2 {+-} 3.1, 12 {+-} 5.9, and 12 {+-} 7.8 Gy for RT-TT with a 2-mm target margin, and 5.3 {+-} 2.3, 11.9 {+-} 5.0, and 12 {+-} 5.6 Gy for 4D-IP, respectively. Conclusion: The results of our study have shown that 4D-IP can achieve plans similar to those achieved by RT-TT. Considering clinical implementation, 4D-IP could be a more reliable and practical method to manage patient respiration-induced motion.},

  doi          = {10.1016/j.ijrobp.2008.07.025},

  url          = {https://www.osti.gov/biblio/21172478},
  journal      = {International Journal of Radiation Oncology, Biology and Physics},

  issn         = {0360-3016},

  number       = 4,

  volume       = 72,

  place        = {United States},

  year         = {Sat Nov 15 00:00:00 EST 2008},

  month        = {Sat Nov 15 00:00:00 EST 2008}

}

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