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Title: Combined kV and MV imaging for real-time tracking of implanted fiducial markers

Abstract

In the presence of intrafraction organ motion, target localization uncertainty can greatly hamper the advantage of highly conformal dose techniques such as intensity modulated radiation therapy (IMRT). To minimize the adverse dosimetric effect caused by tumor motion, a real-time knowledge of the tumor position is required throughout the beam delivery process. The recent integration of onboard kV diagnostic imaging together with MV electronic portal imaging devices on linear accelerators can allow for real-time three-dimensional (3D) tumor position monitoring during a treatment delivery. The aim of this study is to demonstrate a near real-time 3D internal fiducial tracking system based on the combined use of kV and MV imaging. A commercially available radiotherapy system equipped with both kV and MV imaging systems was used in this work. A hardware video frame grabber was used to capture both kV and MV video streams simultaneously through independent video channels at 30 frames per second. The fiducial locations were extracted from the kV and MV images using a software tool. The geometric tracking capabilities of the system were evaluated using a pelvic phantom with embedded fiducials placed on a moveable stage. The maximum tracking speed of the kV/MV system is approximately 9 Hz, whichmore » is primarily limited by the frame rate of the MV imager. The geometric accuracy of the system is found to be on the order of less than 1 mm in all three spatial dimensions. The technique requires minimal hardware modification and is potentially useful for image-guided radiation therapy systems.« less

Authors:
; ;  [1]
  1. Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305-5847 (United States)
Publication Date:
OSTI Identifier:
21120630
Resource Type:
Journal Article
Journal Name:
Medical Physics
Additional Journal Information:
Journal Volume: 35; Journal Issue: 4; Other Information: DOI: 10.1118/1.2842072; (c) 2008 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ACCURACY; COMPUTER CODES; DOSIMETRY; IMAGES; LINEAR ACCELERATORS; NEOPLASMS; PHANTOMS; RADIATION DOSES; RADIOTHERAPY

Citation Formats

Wiersma, R D, Weihua, Mao, and Xing, L. Combined kV and MV imaging for real-time tracking of implanted fiducial markers. United States: N. p., 2008. Web. doi:10.1118/1.2842072.
Wiersma, R D, Weihua, Mao, & Xing, L. Combined kV and MV imaging for real-time tracking of implanted fiducial markers. United States. https://doi.org/10.1118/1.2842072
Wiersma, R D, Weihua, Mao, and Xing, L. 2008. "Combined kV and MV imaging for real-time tracking of implanted fiducial markers". United States. https://doi.org/10.1118/1.2842072.
@article{osti_21120630,
title = {Combined kV and MV imaging for real-time tracking of implanted fiducial markers},
author = {Wiersma, R D and Weihua, Mao and Xing, L},
abstractNote = {In the presence of intrafraction organ motion, target localization uncertainty can greatly hamper the advantage of highly conformal dose techniques such as intensity modulated radiation therapy (IMRT). To minimize the adverse dosimetric effect caused by tumor motion, a real-time knowledge of the tumor position is required throughout the beam delivery process. The recent integration of onboard kV diagnostic imaging together with MV electronic portal imaging devices on linear accelerators can allow for real-time three-dimensional (3D) tumor position monitoring during a treatment delivery. The aim of this study is to demonstrate a near real-time 3D internal fiducial tracking system based on the combined use of kV and MV imaging. A commercially available radiotherapy system equipped with both kV and MV imaging systems was used in this work. A hardware video frame grabber was used to capture both kV and MV video streams simultaneously through independent video channels at 30 frames per second. The fiducial locations were extracted from the kV and MV images using a software tool. The geometric tracking capabilities of the system were evaluated using a pelvic phantom with embedded fiducials placed on a moveable stage. The maximum tracking speed of the kV/MV system is approximately 9 Hz, which is primarily limited by the frame rate of the MV imager. The geometric accuracy of the system is found to be on the order of less than 1 mm in all three spatial dimensions. The technique requires minimal hardware modification and is potentially useful for image-guided radiation therapy systems.},
doi = {10.1118/1.2842072},
url = {https://www.osti.gov/biblio/21120630}, journal = {Medical Physics},
issn = {0094-2405},
number = 4,
volume = 35,
place = {United States},
year = {Tue Apr 15 00:00:00 EDT 2008},
month = {Tue Apr 15 00:00:00 EDT 2008}
}