Experiences in US-Guided Percutaneous Radiofrequency Ablation of 44 Renal Tumors in 31 Patients: Analysis of Predictors for Complications and Technical Success
Abstract
Purpose. Preliminary clinical studies have shown the feasibility, safety, and efficacy of radiofrequency thermal ablation (RFA) of renal tumors, but only a few have analyzed the prognostic factors for technical success and there are no long-term results. Our objective was to statistically evaluate our mid-term results of percutaneous US-guided RFA in order to define predictors for complications and technical success. Methods. We selected for treatment 44 tumors in 31 patients (24 with renal cell carcinoma, 7 with hereditary tumors, 15 with a solitary kidney), up to 5 cm in diameter. Results. Eight adverse events occurred; 3 (6.8%) were major complications, successfully treated with interventional radiology procedures in 2 cases. Exophytic extension of the tumor was protective against complications (p 0.040). Technical success was obtained in 38 lesions after one RFA session and in 39 (89%) after one more session, when possible. At the end of treatment, central extension was the only negative predictor for technical success (p = 0.007), while neither size >3 cm (p = 0.091) nor other prognostic factors were statistically significant. Conclusion. US-guided percutaneous RFA can be proposed for non-central renal tumors up to 5 cm, also in patients without surgical contraindications, thanks to a low incidencemore »
- Authors:
-
- University of Turin, Institute of Diagnostic and Interventional Radiology (Italy)
- University of Turin, Unit of Cancer Epidemiology (Italy)
- San Giovanni Battista Hospital, Unit of Urology (Italy)
- University of Turin, Institute of Urology (Italy)
- Publication Date:
- OSTI Identifier:
- 21091134
- Resource Type:
- Journal Article
- Journal Name:
- Cardiovascular and Interventional Radiology
- Additional Journal Information:
- Journal Volume: 29; Journal Issue: 5; Other Information: DOI: 10.1007/s00270-005-0261-3; Copyright (c) 2006 Springer Science+Business Media, Inc.; www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0174-1551
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 62 RADIOLOGY AND NUCLEAR MEDICINE; ABLATION; BIOMEDICAL RADIOGRAPHY; CARCINOMAS; KIDNEYS; PATIENTS; RADIOWAVE RADIATION; SURGERY
Citation Formats
Veltri, Andrea, Calvo, Amedeo, Tosetti, Irene, Pagano, Eva, Genovesio, Andrea, Virzi, Valentina, Ferrando, Ugo, Fontana, Dario, and Gandini, Giovanni. Experiences in US-Guided Percutaneous Radiofrequency Ablation of 44 Renal Tumors in 31 Patients: Analysis of Predictors for Complications and Technical Success. United States: N. p., 2006.
Web. doi:10.1007/S00270-005-0261-3.
Veltri, Andrea, Calvo, Amedeo, Tosetti, Irene, Pagano, Eva, Genovesio, Andrea, Virzi, Valentina, Ferrando, Ugo, Fontana, Dario, & Gandini, Giovanni. Experiences in US-Guided Percutaneous Radiofrequency Ablation of 44 Renal Tumors in 31 Patients: Analysis of Predictors for Complications and Technical Success. United States. https://doi.org/10.1007/S00270-005-0261-3
Veltri, Andrea, Calvo, Amedeo, Tosetti, Irene, Pagano, Eva, Genovesio, Andrea, Virzi, Valentina, Ferrando, Ugo, Fontana, Dario, and Gandini, Giovanni. 2006.
"Experiences in US-Guided Percutaneous Radiofrequency Ablation of 44 Renal Tumors in 31 Patients: Analysis of Predictors for Complications and Technical Success". United States. https://doi.org/10.1007/S00270-005-0261-3.
@article{osti_21091134,
title = {Experiences in US-Guided Percutaneous Radiofrequency Ablation of 44 Renal Tumors in 31 Patients: Analysis of Predictors for Complications and Technical Success},
author = {Veltri, Andrea and Calvo, Amedeo and Tosetti, Irene and Pagano, Eva and Genovesio, Andrea and Virzi, Valentina and Ferrando, Ugo and Fontana, Dario and Gandini, Giovanni},
abstractNote = {Purpose. Preliminary clinical studies have shown the feasibility, safety, and efficacy of radiofrequency thermal ablation (RFA) of renal tumors, but only a few have analyzed the prognostic factors for technical success and there are no long-term results. Our objective was to statistically evaluate our mid-term results of percutaneous US-guided RFA in order to define predictors for complications and technical success. Methods. We selected for treatment 44 tumors in 31 patients (24 with renal cell carcinoma, 7 with hereditary tumors, 15 with a solitary kidney), up to 5 cm in diameter. Results. Eight adverse events occurred; 3 (6.8%) were major complications, successfully treated with interventional radiology procedures in 2 cases. Exophytic extension of the tumor was protective against complications (p 0.040). Technical success was obtained in 38 lesions after one RFA session and in 39 (89%) after one more session, when possible. At the end of treatment, central extension was the only negative predictor for technical success (p = 0.007), while neither size >3 cm (p = 0.091) nor other prognostic factors were statistically significant. Conclusion. US-guided percutaneous RFA can be proposed for non-central renal tumors up to 5 cm, also in patients without surgical contraindications, thanks to a low incidence of complications and a high success rate. Randomized controlled trials versus surgery are now needed to investigate long-term comparative results.},
doi = {10.1007/S00270-005-0261-3},
url = {https://www.osti.gov/biblio/21091134},
journal = {Cardiovascular and Interventional Radiology},
issn = {0174-1551},
number = 5,
volume = 29,
place = {United States},
year = {Sun Oct 15 00:00:00 EDT 2006},
month = {Sun Oct 15 00:00:00 EDT 2006}
}