Use of the Trellis{sup TM} Peripheral Infusion System for Enhancement of rt-PA Thrombolysis in Acute Lower Limb Ischemia

Journal Article · Sat Nov 15 00:00:00 EST 2003 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-003-0033-X· OSTI ID:21088327

Katsamouris, Asterios N ^[1]; Androulakakis, Zacharias ^[2]; Chamalakis, Konstantinos ^[3]; Kostas, Theodoros ^[1]; Chlapoutakis, Konstantinos; Gourtsoyiannis, Nicholas C ^[3]

---

1. University Hospital of Heraklion, Medical School of Crete, Heraklion, Division of Vascular Surgery (Greece)
2. Venizelion Hospital Heraklion, Crete, Department of Surgery (Greece)
3. University Hospital of Heraklion, Medical School of Crete, Heraklion, Department of Radiology (Greece)

The Trellis{sup TM} Peripheral Infusion System is an over-the-wire 0.035'' guidewire compatible device, designed to isolate a region of the peripheral vasculature to allow for lytic drug infusion and dispersion. We used it successfully through a percutaneous approach in two cases of acute thrombosis of a native lower limb artery. The total amount of rt-PA used was 12 and 9 mg, respectively and was delivered through bolus injections obviating the need for a supplementary continuous infusion of the agent. The time for dissolution of thrombus was 45 and 35 minutes, respectively. No complications were observed.

• OSTI ID: 21088327
• Journal Information: Cardiovascular and Interventional Radiology, Vol. 26, Issue 6; Other Information: DOI: 10.1007/s00270-003-0033-x; Copyright (c) 2003 Springer-Verlag; Article Copyright (c) 2003 Springer-Verlag New York, Inc.; www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
DISSOLUTION
DRUGS
INFUSION
INJECTION
ISCHEMIA
LIMBS
THROMBOSIS