Management of Biliary Neoplastic Obstruction with Two Different Metallic Stents Implanted in One Session

Journal Article · Sat Jan 15 00:00:00 EST 2005 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-004-0082-9· OSTI ID:21088156

Gandini, Roberto; Fabiano, S; Pipitone, Vincenzo; Spinelli, Alessio; Reale, Carlo Andrea; Colangelo, Vittorio; Pampana, Enrico; Romagnoli, Andrea; Simonetti, Giovanni ^[1]

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1. University of Rome 'Tor Vergata', Department of Diagnostic Imaging and Interventional Radiology (Italy)

The efficacy of the 'one-step' technique using two different metallic stents (Wallstent and Ultraflex) and associated rate of complications was studied in 87 patients with jaundice secondary to malignant biliary obstruction, with bilirubin level less than 15 mg/dl and Bismuth type 1 or 2 strictures. The study group, composed of 40 men and 47 women with a mean age of 59.4 years (range 37-81 years), was treated with a 'one-step' percutaneous transhepatic implantation of self-expanding stents. The cause of the obstruction was pancreatic carcinoma in 38 patients (44%), lymph node metastasis in 20 patients (23%), gallbladder carcinoma in 13 patients (15%), cholangiocarcinoma in 12 patients (14%) and ampullary carcinoma in four patients (5%). A significant reduction in jaundice was obtained in all but one patient, with a drop of total serum bilirubin level from a mean of 13.7 mg/dl to 4.3 mg/dl within the first 4 days. The mean postprocedural hospitalization period was 5.4 days in the Wallstent group and 6.4 days in the Ultraflex group. Mean survival rate was 7.8 months (Wallstent group) and 7.1 months (Ultraflex group). The use of both stents did not reveal any significant difference in parameters tested. The implantation of these self-expandable stents in one session, in selected patients, is clinically effective, devoid of important complications and cost-effective due to the reduction in hospitalization.

• OSTI ID: 21088156
• Journal Information: Cardiovascular and Interventional Radiology, Vol. 28, Issue 1; Other Information: DOI: 10.1007/s00270-004-0082-9; Copyright (c) 2005 Springer Science+Business Media, Inc.; Article Copyright (c) 2004 Springer-Verlag New York, LLC.; www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BILIARY TRACT
BILIRUBIN
BISMUTH
CARCINOMAS
JAUNDICE
LYMPH NODES
METASTASES
PANCREAS
PATIENTS