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Title: Results of radiotherapy for Peyronie's disease

Abstract

Purpose: To retrospectively review the results of radiotherapy for Peyronie's disease. Patients and Methods: In the time interval 1983-2000, 154 patients in our clinic were irradiated for Peyronie's disease. Of those, 101 had at least one complete follow-up data set and are the subject of this study. In the majority of patients, penis deviation was between 30 and 50{sup o}, there were one or two indurated foci with a diameter between 5 and 15 mm. Pain was recorded in 48/92 patients. Seventy-two of the 101 patients received radiotherapy with a total dose of 30 Gy, and 25 received 36 Gy in daily fractions of 2.0 Gy. The remaining patients received the following dosage: 34 Gy (1 patient), 38-40 Gy (3 patients). Mean duration of follow-up was 5 years. Results: The best results ever at any time during follow-up were an improvement of deviation in 47%, reduction of number of foci in 32%, reduction of size of foci in 49%, and less induration in 52%. Approximately 50% reported pain relief after radiotherapy. There were 28 patients with mild acute dermatitis and only 4 patients with mild urethritis. There were no long-term side effects. Conclusion: Our results compare well with those ofmore » other studies in the literature. In our patient cohort, radiotherapy was an effective therapy option with only very rare and mild side effects.« less

Authors:
 [1];  [1];  [1];  [1];  [2];  [1]
  1. Clinic for Radiooncology, Saarland University Hospital, Homburg (Germany)
  2. Clinic for Urology and Pediatric Urology, Saarland University Hospital, Homburg (Germany)
Publication Date:
OSTI Identifier:
20788293
Resource Type:
Journal Article
Journal Name:
International Journal of Radiation Oncology, Biology and Physics
Additional Journal Information:
Journal Volume: 64; Journal Issue: 1; Other Information: DOI: 10.1016/j.ijrobp.2005.06.009; PII: S0360-3016(05)01129-6; Copyright (c) 2006 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0360-3016
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; DERMATITIS; IRRADIATION; PAIN; PATIENTS; RADIOTHERAPY; SIDE EFFECTS

Citation Formats

Niewald, Marcus, Wenzlawowicz, Knut v, Fleckenstein, Jochen, Wisser, Lothar, Derouet, Harry, and Ruebe, Christian. Results of radiotherapy for Peyronie's disease. United States: N. p., 2006. Web. doi:10.1016/J.IJROBP.2005.0.
Niewald, Marcus, Wenzlawowicz, Knut v, Fleckenstein, Jochen, Wisser, Lothar, Derouet, Harry, & Ruebe, Christian. Results of radiotherapy for Peyronie's disease. United States. https://doi.org/10.1016/J.IJROBP.2005.0
Niewald, Marcus, Wenzlawowicz, Knut v, Fleckenstein, Jochen, Wisser, Lothar, Derouet, Harry, and Ruebe, Christian. 2006. "Results of radiotherapy for Peyronie's disease". United States. https://doi.org/10.1016/J.IJROBP.2005.0.
@article{osti_20788293,
title = {Results of radiotherapy for Peyronie's disease},
author = {Niewald, Marcus and Wenzlawowicz, Knut v and Fleckenstein, Jochen and Wisser, Lothar and Derouet, Harry and Ruebe, Christian},
abstractNote = {Purpose: To retrospectively review the results of radiotherapy for Peyronie's disease. Patients and Methods: In the time interval 1983-2000, 154 patients in our clinic were irradiated for Peyronie's disease. Of those, 101 had at least one complete follow-up data set and are the subject of this study. In the majority of patients, penis deviation was between 30 and 50{sup o}, there were one or two indurated foci with a diameter between 5 and 15 mm. Pain was recorded in 48/92 patients. Seventy-two of the 101 patients received radiotherapy with a total dose of 30 Gy, and 25 received 36 Gy in daily fractions of 2.0 Gy. The remaining patients received the following dosage: 34 Gy (1 patient), 38-40 Gy (3 patients). Mean duration of follow-up was 5 years. Results: The best results ever at any time during follow-up were an improvement of deviation in 47%, reduction of number of foci in 32%, reduction of size of foci in 49%, and less induration in 52%. Approximately 50% reported pain relief after radiotherapy. There were 28 patients with mild acute dermatitis and only 4 patients with mild urethritis. There were no long-term side effects. Conclusion: Our results compare well with those of other studies in the literature. In our patient cohort, radiotherapy was an effective therapy option with only very rare and mild side effects.},
doi = {10.1016/J.IJROBP.2005.0},
url = {https://www.osti.gov/biblio/20788293}, journal = {International Journal of Radiation Oncology, Biology and Physics},
issn = {0360-3016},
number = 1,
volume = 64,
place = {United States},
year = {Sun Jan 01 00:00:00 EST 2006},
month = {Sun Jan 01 00:00:00 EST 2006}
}