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Title: Simultaneous determination of size and refractive index of red blood cells by light scattering measurements

Abstract

We present a fast and accurate approach for simultaneous determination of both the mean diameter and refractive index of a collection of red blood cells (RBCs). The approach uses the peak frequency of the power spectrum and the corresponding phase angle obtained by performing Fourier transform on the measured angular distribution of scattered light to determine these parameters. Results on the measurement of two important clinical parameters, the mean cell volume and mean cell hemoglobin concentration of a collection of RBCs, are presented.

Authors:
; ; ; ; ;  [1]
  1. Biomedical Applications Section, Centre for Advanced Technology, Indore, 452013 (India)
Publication Date:
OSTI Identifier:
20778694
Resource Type:
Journal Article
Journal Name:
Applied Physics Letters
Additional Journal Information:
Journal Volume: 88; Journal Issue: 8; Other Information: DOI: 10.1063/1.2176854; (c) 2006 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0003-6951
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; ANGULAR DISTRIBUTION; BIOPHYSICS; BLOOD CELLS; DIAGNOSIS; FOURIER TRANSFORMATION; HEMOGLOBIN; LIGHT SCATTERING; PATIENTS; REFRACTIVE INDEX

Citation Formats

Ghosh, N, Buddhiwant, P, Uppal, A, Majumder, S K, Patel, H S, and Gupta, P K. Simultaneous determination of size and refractive index of red blood cells by light scattering measurements. United States: N. p., 2006. Web. doi:10.1063/1.2176854.
Ghosh, N, Buddhiwant, P, Uppal, A, Majumder, S K, Patel, H S, & Gupta, P K. Simultaneous determination of size and refractive index of red blood cells by light scattering measurements. United States. https://doi.org/10.1063/1.2176854
Ghosh, N, Buddhiwant, P, Uppal, A, Majumder, S K, Patel, H S, and Gupta, P K. 2006. "Simultaneous determination of size and refractive index of red blood cells by light scattering measurements". United States. https://doi.org/10.1063/1.2176854.
@article{osti_20778694,
title = {Simultaneous determination of size and refractive index of red blood cells by light scattering measurements},
author = {Ghosh, N and Buddhiwant, P and Uppal, A and Majumder, S K and Patel, H S and Gupta, P K},
abstractNote = {We present a fast and accurate approach for simultaneous determination of both the mean diameter and refractive index of a collection of red blood cells (RBCs). The approach uses the peak frequency of the power spectrum and the corresponding phase angle obtained by performing Fourier transform on the measured angular distribution of scattered light to determine these parameters. Results on the measurement of two important clinical parameters, the mean cell volume and mean cell hemoglobin concentration of a collection of RBCs, are presented.},
doi = {10.1063/1.2176854},
url = {https://www.osti.gov/biblio/20778694}, journal = {Applied Physics Letters},
issn = {0003-6951},
number = 8,
volume = 88,
place = {United States},
year = {Mon Feb 20 00:00:00 EST 2006},
month = {Mon Feb 20 00:00:00 EST 2006}
}