Functional One-Dimensional Lipid Bilayers on Carbon Nanotube Templates

Journal Article · Fri Jul 23 00:00:00 EDT 2004 · Journal of the American Chemical Society

OSTI ID:15020090

Artyukhin, A; Shestakov, A; Harper, J; Bakajin, O; Stroeve, P; Noy, A

We present one-dimensional (1-D) lipid bilayer structures that integrate carbon nanotubes with a key biological environment-phospholipid membrane. Our structures consist of lipid bilayers wrapped around carbon nanotubes modified with a hydrophilic polymer cushion layer. Despite high bilayer curvature, the lipid membrane maintains its fluidity and can sustain repeated damage-recovery cycles. We also present the first evidence of spontaneous insertion of pore-forming proteins into 1-D lipid bilayers. These structures could lead to the development of new classes of biosensors and bioelectronic devices.

• Research Organization: Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
• Sponsoring Organization: USDOE
• DOE Contract Number: W-7405-ENG-48
• OSTI ID: 15020090
• Report Number(s): UCRL-JRNL-205932; JACSAT; TRN: US200519%%174
• Journal Information: Journal of the American Chemical Society, Vol. 127, Issue 20; ISSN 0002-7863
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
59 BASIC BIOLOGICAL SCIENCES
CARBON
FUNCTIONALS
LIPIDS
MEMBRANES
NANOTUBES
POLYMERS
PROTEINS