A Comprehensive Approach for Accurate Measurement of Proton-Proton Coupling Constants in the Sugar Ring of DNA
Abstract
Stereo-selective deuteration has been explored in the 12 base pair DNA Dickerson sequence [d(CGCGAATTCGCG)2] as an approach for improving the accuracy of NMR derived, three-bond vicinal proton-proton coupling constants. The coupling constants are useful for DNA structure determination in restrained molecular dynamics calculations.
- Authors:
- Publication Date:
- Research Org.:
- Pacific Northwest National Lab., Richland, WA (US), Environmental Molecular Sciences Laboratory (US)
- Sponsoring Org.:
- US Department of Energy (US)
- OSTI Identifier:
- 15011348
- Report Number(s):
- PNNL-SA-32710
Journal ID: ISSN 1090-7807; JMARF3; 1698; 1852; KP1402010; TRN: US200506%%275
- DOE Contract Number:
- AC05-76RL01830
- Resource Type:
- Journal Article
- Journal Name:
- Journal of Magnetic Resonance
- Additional Journal Information:
- Journal Volume: 146; Journal Issue: 2; Other Information: PBD: 1 Oct 2000; Journal ID: ISSN 1090-7807
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; ACCURACY; COUPLING CONSTANTS; DEUTERATION; DNA; SACCHAROSE; ENVIRONMENTAL MOLECULAR SCIENCES LABORATORY
Citation Formats
Yang, Jiping, McAteer, Kathleen, Silks, Louis A, Wu, Ruilian, Isern, Nancy G, Unkefer, Clifford J, and Kennedy, Michael A. A Comprehensive Approach for Accurate Measurement of Proton-Proton Coupling Constants in the Sugar Ring of DNA. United States: N. p., 2000.
Web. doi:10.1006/jmre.2000.2154.
Yang, Jiping, McAteer, Kathleen, Silks, Louis A, Wu, Ruilian, Isern, Nancy G, Unkefer, Clifford J, & Kennedy, Michael A. A Comprehensive Approach for Accurate Measurement of Proton-Proton Coupling Constants in the Sugar Ring of DNA. United States. https://doi.org/10.1006/jmre.2000.2154
Yang, Jiping, McAteer, Kathleen, Silks, Louis A, Wu, Ruilian, Isern, Nancy G, Unkefer, Clifford J, and Kennedy, Michael A. 2000.
"A Comprehensive Approach for Accurate Measurement of Proton-Proton Coupling Constants in the Sugar Ring of DNA". United States. https://doi.org/10.1006/jmre.2000.2154.
@article{osti_15011348,
title = {A Comprehensive Approach for Accurate Measurement of Proton-Proton Coupling Constants in the Sugar Ring of DNA},
author = {Yang, Jiping and McAteer, Kathleen and Silks, Louis A and Wu, Ruilian and Isern, Nancy G and Unkefer, Clifford J and Kennedy, Michael A},
abstractNote = {Stereo-selective deuteration has been explored in the 12 base pair DNA Dickerson sequence [d(CGCGAATTCGCG)2] as an approach for improving the accuracy of NMR derived, three-bond vicinal proton-proton coupling constants. The coupling constants are useful for DNA structure determination in restrained molecular dynamics calculations.},
doi = {10.1006/jmre.2000.2154},
url = {https://www.osti.gov/biblio/15011348},
journal = {Journal of Magnetic Resonance},
issn = {1090-7807},
number = 2,
volume = 146,
place = {United States},
year = {Sun Oct 01 00:00:00 EDT 2000},
month = {Sun Oct 01 00:00:00 EDT 2000}
}
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