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Title: Improvements to PATRIC, the all-bacterial Bioinformatics Database and Analysis Resource Center

Journal Article · · Nucleic Acids Research
DOI:https://doi.org/10.1093/nar/gkw1017· OSTI ID:1373595

Here, the Pathosystems Resource Integration Center (PATRIC) is the bacterial Bioinformatics Resource Center. Recent changes to PATRIC include a redesign of the web interface and some new services that provide users with a platform that takes them from raw reads to an integrated analysis experience. The redesigned interface allows researchers direct access to tools and data, and the emphasis has changed to user-created genome-groups, with detailed summaries and views of the data that researchers have selected. Perhaps the biggest change has been the enhanced capability for researchers to analyze their private data and compare it to the available public data. Researchers can assemble their raw sequence reads and annotate the contigs using RASTtk. PATRIC also provides services for RNA-Seq, variation, model reconstruction and differential expression analysis, all delivered through an updated private workspace. Private data can be compared by `virtual integration' to any of PATRIC's public data. The number of genomes available for comparison in PATRIC has expanded to over 80 000, with a special emphasis on genomes with antimicrobial resistance data. PATRIC uses this data to improve both subsystem annotation and k-mer classification, and tags new genomes as having signatures that indicate susceptibility or resistance to specific antibiotics.

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States)
Sponsoring Organization:
National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID)
Grant/Contract Number:
AC02-06CH11357
OSTI ID:
1373595
Journal Information:
Nucleic Acids Research, Vol. 45, Issue D1; ISSN 0305-1048
Publisher:
Oxford University PressCopyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 871 works
Citation information provided by
Web of Science

References (48)

PATRIC, the bacterial bioinformatics database and analysis resource journal November 2013
Type material in the NCBI Taxonomy Database journal November 2014
Genome-wide analysis of the interaction between the endosymbiotic bacterium Wolbachia and its Drosophila host journal January 2008
RASTtk: A modular and extensible implementation of the RAST algorithm for building custom annotation pipelines and annotating batches of genomes journal February 2015
The sequence read archive: explosive growth of sequencing data journal October 2011
GenBank journal November 2015
Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation journal November 2015
De novo genome assembly: what every biologist should know journal March 2012
PacBio Sequencing and Its Applications journal October 2015
The potential and challenges of nanopore sequencing journal October 2008
Assessing the performance of the Oxford Nanopore Technologies MinION journal March 2015
The complex transcriptional landscape of the anucleate human platelet journal January 2013
MetaVelvet: an extension of Velvet assembler to de novo metagenome assembly from short sequence reads journal July 2012
Velvet: Algorithms for de novo short read assembly using de Bruijn graphs journal February 2008
SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing journal May 2012
MEGAHIT: an ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph journal January 2015
ALE: a generic assembly likelihood evaluation framework for assessing the accuracy of genome and metagenome assemblies journal January 2013
QUAST: quality assessment tool for genome assemblies journal February 2013
NCBI BLAST: a better web interface journal May 2008
ARDB--Antibiotic Resistance Genes Database journal January 2009
VFDB 2016: hierarchical and refined dataset for big data analysis—10 years on journal November 2015
Curation, integration and visualization of bacterial virulence factors in PATRIC journal September 2014
Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information journal November 2015
DrugBank 4.0: shedding new light on drug metabolism journal November 2013
KEGG as a reference resource for gene and protein annotation journal October 2015
Antimicrobial Resistance Prediction in PATRIC and RAST journal June 2016
Computational analysis of bacterial RNA-Seq data journal May 2013
Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks journal March 2012
RNA-Rocket: an RNA-Seq analysis resource for infectious disease research journal January 2015
Fast and accurate short read alignment with Burrows-Wheeler transform journal May 2009
Fast gapped-read alignment with Bowtie 2 journal March 2012
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome journal January 2009
MOSAIK: A Hash-Based Algorithm for Accurate Next-Generation Sequencing Short-Read Mapping journal March 2014
Incorporating sequence quality data into alignment improves DNA read mapping journal January 2010
The Sequence Alignment/Map format and SAMtools journal June 2009
High-throughput generation, optimization and analysis of genome-scale metabolic models journal August 2010
The European Nucleotide Archive journal October 2010
OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups journal January 2006
FIGfams: yet another set of protein families journal September 2009
The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology (RAST) journal November 2013
The Subsystems Approach to Genome Annotation and its Use in the Project to Annotate 1000 Genomes journal September 2005
PATtyFams: Protein Families for the Microbial Genomes in the PATRIC Database journal February 2016
Mutations in virus-derived small RNAs journal June 2020
RNA-Rocket: An RNA-Seq Analysis Resource for Infectious Disease Research journal August 2014
The potential and challenges of nanopore sequencing text January 2008
MOSAIK: A hash-based algorithm for accurate next-generation sequencing read mapping text January 2013
MEGAHIT: An ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph preprint January 2014
The need for speed journal January 2009

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