Computational design of microscopic swimmers and capsules: From directed motion to collective behavior

Nikolov, Svetoslav V.; Shum, Henry; Balazs, Anna C.; Alexeev, Alexander

doi:10.1016/j.cocis.2015.10.012

Title: Computational design of microscopic swimmers and capsules: From directed motion to collective behavior

Journal Article · Mon Feb 01 00:00:00 EST 2016 · Current Opinion in Colloid & Interface Science

DOI:https://doi.org/10.1016/j.cocis.2015.10.012· OSTI ID:1370836

Nikolov, Svetoslav V.; Shum, Henry; Balazs, Anna C.; Alexeev, Alexander

Systems of motile microscopic particles can exhibit behaviors that resemble those of living microorganisms, including cooperative motion, self-organization, and adaptability to changing environments. Using mesoscale computational modeling, we design synthetic microswimmers and microcapsules that undergo controllable, self-propelled motion in solution. Stimuli-responsive hydrogels are used to actuate the microswimmers and to enable their navigation and chemotaxing behavior. The self-propelled motion of microcapsules on solid surfaces is achieved by the release of encapsulated solutes that alter the surface adhesiveness. These signaling solutes also enable interactions among multiple microcapsules that lead to complex, cooperative behavior. Our findings provide guidelines for creating microscopic devices and machines able to autonomously move and mimic the communication and chemotaxis of biological microorganisms.

Cite

Export

Save

Research Organization:: Energy Frontier Research Centers (EFRC) (United States). Center for Bio-Inspired Energy Science (CBES)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

DOE Contract Number:: SC0000989

OSTI ID:: 1370836

Journal Information:: Current Opinion in Colloid & Interface Science, Vol. 21, Issue C; Related Information: CBES partners with Northwestern University (lead); Harvard University; New York University; Pennsylvania State University; University of Michigan; University of Pittsburgh; ISSN 1359-0294

Publisher:: Elsevier

Country of Publication:: United States

Language:: English

References (78)

Transcriptome of Swarming Proteus mirabilis Pearson, Melanie M.; Rasko, David A.; Smith, Sara N. Infection and Immunity, Vol. 78, Issue 6 https://doi.org/10.1128/IAI.01222-09	journal	April 2010
Moving to the beat: a review of mammalian sperm motility regulation Turner, Regina M. Reproduction, Fertility and Development, Vol. 18, Issue 2 https://doi.org/10.1071/RD05120	journal	January 2006
Physics of microswimmers—single particle motion and collective behavior: a review Elgeti, J.; Winkler, R. G.; Gompper, G. Reports on Progress in Physics, Vol. 78, Issue 5 https://doi.org/10.1088/0034-4885/78/5/056601	journal	April 2015
Bacterial rheotaxis Proceedings of the National Academy of Sciences, Vol. 109, Issue 13 https://doi.org/10.1073/pnas.1120955109	journal	March 2012
Communication in bacteria: an ecological and evolutionary perspective Keller, Laurent; Surette, Michael G. Nature Reviews Microbiology, Vol. 4, Issue 4 https://doi.org/10.1038/nrmicro1383	journal	February 2006
Social evolution theory for microorganisms West, Stuart A.; Griffin, Ashleigh S.; Gardner, Andy Nature Reviews Microbiology, Vol. 4, Issue 8 https://doi.org/10.1038/nrmicro1461	journal	August 2006
Synthetic biology, inspired by synthetic chemistry Malinova, V.; Nallani, M.; Meier, W. P. FEBS Letters, Vol. 586, Issue 15 https://doi.org/10.1016/j.febslet.2012.05.033	journal	June 2012
Microrobots for Minimally Invasive Medicine Nelson, Bradley J.; Kaliakatsos, Ioannis K.; Abbott, Jake J. Annual Review of Biomedical Engineering, Vol. 12, Issue 1 https://doi.org/10.1146/annurev-bioeng-010510-103409	journal	July 2010
Engineering microbial consortia: a new frontier in synthetic biology Brenner, Katie; You, Lingchong; Arnold, Frances H. Trends in Biotechnology, Vol. 26, Issue 9, p. 483-489 https://doi.org/10.1016/j.tibtech.2008.05.004	journal	September 2008
Engineering Escherichia coli to see light Levskaya, Anselm; Chevalier, Aaron A.; Tabor, Jeffrey J. Nature, Vol. 438, Issue 7067 https://doi.org/10.1038/nature04405	journal	November 2005
Synthetic micro/nanomotors in drug delivery Gao, Wei; Wang, Joseph Nanoscale, Vol. 6, Issue 18 https://doi.org/10.1039/C4NR03124E	journal	January 2014
Propulsion of an artificial nanoswimmer: a comprehensive review Nain, Shivani; Sharma, N. N. Frontiers in Life Science, Vol. 8, Issue 1 https://doi.org/10.1080/21553769.2014.962103	journal	October 2014
Magnetic Helical Micromachines: Fabrication, Controlled Swimming, and Cargo Transport Tottori, Soichiro; Zhang, Li; Qiu, Famin Advanced Materials, Vol. 24, Issue 6 https://doi.org/10.1002/adma.201103818	journal	January 2012
The hydrodynamics of swimming microorganisms Lauga, Eric; Powers, Thomas R. Reports on Progress in Physics, Vol. 72, Issue 9 https://doi.org/10.1088/0034-4885/72/9/096601	journal	August 2009
Fantastic Voyage: Designing Self-Powered Nanorobots Sengupta, Samudra; Ibele, Michael E.; Sen, Ayusman Angewandte Chemie International Edition, Vol. 51, Issue 34 https://doi.org/10.1002/anie.201202044	journal	August 2012
Enzymatically induced motion at nano- and micro-scales Gáspár, Szilveszter Nanoscale, Vol. 6, Issue 14 https://doi.org/10.1039/C4NR01760A	journal	January 2014
Autonomous movement of platinum-loaded stomatocytes Wilson, Daniela A.; Nolte, Roeland J. M.; van Hest, Jan C. M. Nature Chemistry, Vol. 4, Issue 4 https://doi.org/10.1038/nchem.1281	journal	February 2012
Nanopropellers and Their Actuation in Complex Viscoelastic Media Schamel, Debora; Mark, Andrew G.; Gibbs, John G. ACS Nano, Vol. 8, Issue 9 https://doi.org/10.1021/nn502360t	journal	June 2014
Nano/Micromotors in (Bio)chemical Science Applications Guix, Maria; Mayorga-Martinez, Carmen C.; Merkoçi, Arben Chemical Reviews, Vol. 114, Issue 12 https://doi.org/10.1021/cr400273r	journal	April 2014
Catalytic Mesoporous Janus Nanomotors for Active Cargo Delivery Ma, Xing; Hahn, Kersten; Sanchez, Samuel Journal of the American Chemical Society, Vol. 137, Issue 15 https://doi.org/10.1021/jacs.5b02700	journal	April 2015
Bioinspired Helical Microswimmers Based on Vascular Plants Gao, Wei; Feng, Xiaomiao; Pei, Allen Nano Letters, Vol. 14, Issue 1 https://doi.org/10.1021/nl404044d	journal	December 2013
Selectively manipulable acoustic-powered microswimmers Ahmed, Daniel; Lu, Mengqian; Nourhani, Amir Scientific Reports, Vol. 5, Issue 1 https://doi.org/10.1038/srep09744	journal	May 2015
A review of stimuli-responsive shape memory polymer composites Meng, Harper; Li, Guoqiang Polymer, Vol. 54, Issue 9 https://doi.org/10.1016/j.polymer.2013.02.023	journal	April 2013
Stimuli-responsive polymer gels Ahn, Suk-kyun; Kasi, Rajeswari M.; Kim, Seong-Cheol Soft Matter, Vol. 4, Issue 6 https://doi.org/10.1039/b714376a	journal	January 2008
Environment-sensitive hydrogels for drug delivery Qiu, Yong; Park, Kinam Advanced Drug Delivery Reviews, Vol. 64 https://doi.org/10.1016/j.addr.2012.09.024	journal	December 2012
Soft and Wet Materials: Polymer Gels Osada, Yoshihito; Gong, Jian-Ping Advanced Materials, Vol. 10, Issue 11, p. 827-837 https://doi.org/10.1002/(SICI)1521-4095(199808)10:11<827::AID-ADMA827>3.0.CO;2-L	journal	August 1998
Self-Propelled Microswimmer Actuated by Stimuli-Sensitive Bilayered Hydrogel Nikolov, Svetoslav V.; Yeh, Peter D.; Alexeev, Alexander ACS Macro Letters, Vol. 4, Issue 1 https://doi.org/10.1021/mz5007014	journal	December 2014
Designing maneuverable micro-swimmers actuated by responsive gel Masoud, Hassan; Bingham, Benjamin I.; Alexeev, Alexander Soft Matter, Vol. 8, Issue 34 https://doi.org/10.1039/c2sm25898f	journal	January 2012
Synthetic running and tumbling: an autonomous navigation strategy for catalytic nanoswimmers Ebbens, Stephen J.; Buxton, Gavin A.; Alexeev, Alexander Soft Matter, Vol. 8, Issue 11 https://doi.org/10.1039/c2sm07283a	journal	January 2012
Behavioral Responses in Bacteria Armitage, J. P. Annual Review of Physiology, Vol. 54, Issue 1 https://doi.org/10.1146/annurev.ph.54.030192.003343	journal	October 1992
Polymer hydrogel capsules: en route toward synthetic cellular systems Städler, Brigitte; Price, Andrew D.; Chandrawati, Rona Nanoscale, Vol. 1, Issue 1 https://doi.org/10.1039/b9nr00143c	journal	January 2009
Artificial Cell Based on Lipid Hollow Polyelectrolyte Microcapsules: Channel Reconstruction and Membrane Potential Measurement Tiourina, O. P.; Radtchenko, I.; Sukhorukov, G. B. Journal of Membrane Biology, Vol. 190, Issue 1 https://doi.org/10.1007/s00232-002-1018-4	journal	November 2002
Tailor-Made Polyelectrolyte Microcapsules: From Multilayers to Smart Containers Peyratout, Claire S.; Dähne, Lars Angewandte Chemie International Edition, Vol. 43, Issue 29 https://doi.org/10.1002/anie.200300568	journal	July 2004
Polymersomes: Tough Vesicles Made from Diblock Copolymers Discher, B. M. Science, Vol. 284, Issue 5417 https://doi.org/10.1126/science.284.5417.1143	journal	May 1999
Leuko-polymersomes Hammer, Daniel A.; Robbins, Gregory P.; Haun, Jered B. Faraday Discussions, Vol. 139 https://doi.org/10.1039/b717821b	journal	January 2008
Stimuli-responsive polypeptide vesicles by conformation-specific assembly Bellomo, Enrico G.; Wyrsta, Michael D.; Pakstis, Lisa Nature Materials, Vol. 3, Issue 4 https://doi.org/10.1038/nmat1093	journal	March 2004
Tough and smart Jones, Richard A. L. Nature Materials, Vol. 3, Issue 4 https://doi.org/10.1038/nmat1109	journal	April 2004
Redox-controlled molecular permeability of composite-wall microcapsules Ma, Yujie; Dong, Wen-Fei; Hempenius, Mark A. Nature Materials, Vol. 5, Issue 9 https://doi.org/10.1038/nmat1716	journal	August 2006
pH-Controlled Macromolecule Encapsulation in and Release from Polyelectrolyte Multilayer Nanocapsules Sukhorukov, Gleb B.; Antipov, Alexei A.; Voigt, Andreas Macromolecular Rapid Communications, Vol. 22, Issue 1 https://doi.org/10.1002/1521-3927(20010101)22:1<44::AID-MARC44>3.0.CO;2-U	journal	January 2001
Layer-by-Layer Assembled Nanocontainers for Self-Healing Corrosion Protection Shchukin, D. G.; Zheludkevich, M.; Yasakau, K. Advanced Materials, Vol. 18, Issue 13 https://doi.org/10.1002/adma.200502053	journal	July 2006
Quantification of release from microcapsules upon mechanical deformation with AFM Fernandes, Paulo A. L.; Delcea, Mihaela; Skirtach, Andre G. Soft Matter, Vol. 6, Issue 9 https://doi.org/10.1039/c002564j	journal	January 2010
Manipulating Microparticles with Single Surface-Immobilized Nanoparticles Zhang, Jun; Srivastava, Sudhanshu; Duffadar, Ranojoy Langmuir, Vol. 24, Issue 13 https://doi.org/10.1021/la800857v	journal	July 2008
Engineering Nanoscale Surface Features to Sustain Microparticle Rolling in Flow Kalasin, Surachate; Santore, Maria M. ACS Nano, Vol. 9, Issue 5 https://doi.org/10.1021/nn505322m	journal	March 2015
Designing mechano-responsive microcapsules that undergo self-propelled motion Kolmakov, German V.; Schaefer, Alexander; Aranson, Igor Soft Matter, Vol. 8, Issue 1 https://doi.org/10.1039/C1SM06415K	journal	January 2012
Designing communicating colonies of biomimetic microcapsules Kolmakov, German V.; Yashin, Victor V.; Levitan, Steven P. Proceedings of the National Academy of Sciences, Vol. 107, Issue 28 https://doi.org/10.1073/pnas.1001950107	journal	June 2010
Design rules for creating sensing and self-actuating microcapsules Kolmakov, German V.; Yashin, Victor V.; Balazs, Anna C. Smart Structures and Systems, Vol. 7, Issue 3 https://doi.org/10.12989/sss.2011.7.3.199	journal	March 2011
Self-assembly of microcapsules regulated via the repressilator signaling network Shum, Henry; Yashin, Victor V.; Balazs, Anna C. Soft Matter, Vol. 11, Issue 18 https://doi.org/10.1039/C5SM00201J	journal	January 2015
Designing self-propelled microcapsules for pick-up and delivery of microscopic cargo Kolmakov, German V.; Yashin, Victor V.; Levitan, Steven P. Soft Matter, Vol. 7, Issue 7 https://doi.org/10.1039/c0sm00864h	journal	January 2011
Life at low Reynolds number Purcell, E. M. American Journal of Physics, Vol. 45, Issue 1 https://doi.org/10.1119/1.10903	journal	January 1977
Dissipative particle dynamics: Bridging the gap between atomistic and mesoscopic simulation Groot, Robert D.; Warren, Patrick B. The Journal of Chemical Physics, Vol. 107, Issue 11 https://doi.org/10.1063/1.474784	journal	September 1997
Simulating Microscopic Hydrodynamic Phenomena with Dissipative Particle Dynamics Hoogerbrugge, P. J.; Koelman, J. M. V. A. Europhysics Letters (EPL), Vol. 19, Issue 3 https://doi.org/10.1209/0295-5075/19/3/001	journal	June 1992
Mesoscale modeling: solving complex flows in biology and biotechnology Mills, Zachary Grant; Mao, Wenbin; Alexeev, Alexander Trends in Biotechnology, Vol. 31, Issue 7 https://doi.org/10.1016/j.tibtech.2013.05.001	journal	July 2013
Mesoscale modelling of environmentally responsive hydrogels: emerging applications Yeh, Peter D.; Alexeev, Alexander Chemical Communications, Vol. 51, Issue 50 https://doi.org/10.1039/C5CC01027F	journal	January 2015
Permeability and Diffusion through Mechanically Deformed Random Polymer Networks Masoud, Hassan; Alexeev, Alexander Macromolecules, Vol. 43, Issue 23 https://doi.org/10.1021/ma102052m	journal	December 2010
Controlled Release of Nanoparticles and Macromolecules from Responsive Microgel Capsules Masoud, Hassan; Alexeev, Alexander ACS Nano, Vol. 6, Issue 1 https://doi.org/10.1021/nn2043143	journal	December 2011
Swelling Kinetics of Poly( N -isopropylacrylamide) Minigels Suárez, Iván J.; Fernández-Nieves, Alberto; Márquez, Manuel The Journal of Physical Chemistry B, Vol. 110, Issue 51 https://doi.org/10.1021/jp0643754	journal	December 2006
Self-(Un)rolling Biopolymer Microstructures: Rings, Tubules, and Helical Tubules from the Same Material Ye, Chunhong; Nikolov, Svetoslav V.; Calabrese, Rossella Angewandte Chemie, Vol. 127, Issue 29 https://doi.org/10.1002/ange.201502485	journal	June 2015
Thin Film Assembly of Spider Silk-like Block Copolymers Krishnaji, Sreevidhya T.; Huang, Wenwen; Rabotyagova, Olena Langmuir, Vol. 27, Issue 3 https://doi.org/10.1021/la102638j	journal	February 2011
A lattice spring model of heterogeneous materials with plasticity Buxton, Gavin A.; Care, Christopher M.; Cleaver, Douglas J. Modelling and Simulation in Materials Science and Engineering, Vol. 9, Issue 6 https://doi.org/10.1088/0965-0393/9/6/302	journal	October 2001
Modeling the Motion of Microcapsules on Compliant Polymeric Surfaces Alexeev, Alexander; Verberg, Rolf; Balazs, Anna C. Macromolecules, Vol. 38, Issue 24 https://doi.org/10.1021/ma0516135	journal	November 2005
Trapping and Wiggling: Elastohydrodynamics of Driven Microfilaments Wiggins, Chris H.; Riveline, D.; Ott, A. Biophysical Journal, Vol. 74, Issue 2 https://doi.org/10.1016/S0006-3495(98)74029-9	journal	February 1998
Polarization-controlled, photodriven bending in monodomain liquid crystal elastomer cantilevers White, Timothy J.; Serak, Svetlana V.; Tabiryan, Nelson V. J. Mater. Chem., Vol. 19, Issue 8 https://doi.org/10.1039/B818457G	journal	January 2009
Chemical Locomotion Paxton, Walter F.; Sundararajan, Shakuntala; Mallouk, Thomas E. Angewandte Chemie International Edition, Vol. 45, Issue 33 https://doi.org/10.1002/anie.200600060	journal	August 2006
Size dependence of the propulsion velocity for catalytic Janus-sphere swimmers Ebbens, Stephen; Tu, Mei-Hsien; Howse, Jonathan R. Physical Review E, Vol. 85, Issue 2 https://doi.org/10.1103/PhysRevE.85.020401	journal	February 2012
Swimming efficiency of bacterium Escherichia coli Chattopadhyay, S.; Moldovan, R.; Yeung, C. Proceedings of the National Academy of Sciences, Vol. 103, Issue 37 https://doi.org/10.1073/pnas.0602043103	journal	September 2006
Chemotaxis of Nonbiological Colloidal Rods Hong, Yiying; Blackman, Nicole M. K.; Kopp, Nathaniel D. Physical Review Letters, Vol. 99, Issue 17 https://doi.org/10.1103/PhysRevLett.99.178103	journal	October 2007
Chemical influences on adsorption-mediated self-propelled drop movement Lee, Seok-Won; Kwok, Daniel Y.; Laibinis, Paul E. Physical Review E, Vol. 65, Issue 5 https://doi.org/10.1103/PhysRevE.65.051602	journal	May 2002
The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells Li, Song; Butler, Peter; Wang, Yingxiao Proceedings of the National Academy of Sciences, Vol. 99, Issue 6 https://doi.org/10.1073/pnas.052018099	journal	March 2002
Cell Movement Is Guided by the Rigidity of the Substrate Lo, Chun-Min; Wang, Hong-Bei; Dembo, Micah Biophysical Journal, Vol. 79, Issue 1 https://doi.org/10.1016/S0006-3495(00)76279-5	journal	July 2000
Using Nanoparticle-Filled Microcapsules for Site-Specific Healing of Damaged Substrates: Creating a “Repair-and-Go” System Kolmakov, German V.; Revanur, Ravindra; Tangirala, Ravisubhash ACS Nano, Vol. 4, Issue 2 https://doi.org/10.1021/nn901296y	journal	January 2010
Probing and repairing damaged surfaces with nanoparticle-containing microcapsules Kratz, Katrina; Narasimhan, Amrit; Tangirala, Ravisubhash Nature Nanotechnology, Vol. 7, Issue 2 https://doi.org/10.1038/nnano.2011.235	journal	January 2012
Biomimetic chemical signaling across synthetic microcapsule arrays Bhattacharya, Amitabh; Balazs, Anna C. Journal of Materials Chemistry, Vol. 20, Issue 46 https://doi.org/10.1039/c0jm01682a	journal	January 2010
Designing smart systems to selectively entrap and burst microcapsules Alexeev, Alexander; Balazs, Anna C. Soft Matter, Vol. 3, Issue 12 https://doi.org/10.1039/b711769h	journal	January 2007
Designing microcapsule arrays that propagate chemical signals Bhattacharya, Amitabh; Balazs, Anna C. Physical Review E, Vol. 82, Issue 2 https://doi.org/10.1103/PhysRevE.82.021801	journal	August 2010
Modeling the release of nanoparticles from mobile microcapsules Verberg, Rolf; Alexeev, Alexander; Balazs, Anna C. The Journal of Chemical Physics, Vol. 125, Issue 22 https://doi.org/10.1063/1.2404955	journal	December 2006
Direct-write assembly of biomimetic microvascular networks for efficient fluid transport Wu, Willie; Hansen, Christopher J.; Aragón, Alejandro M. Soft Matter, Vol. 6, Issue 4 https://doi.org/10.1039/B918436H	journal	January 2010
A synthetic oscillatory network of transcriptional regulators Elowitz, Michael B.; Leibler, Stanislas Nature, Vol. 403, Issue 6767 https://doi.org/10.1038/35002125	journal	January 2000
Soft microorigami: self-folding polymer films Ionov, Leonid Soft Matter, Vol. 7, Issue 15 https://doi.org/10.1039/c1sm05476g	journal	January 2011

Similar Records

Autonomous navigation of shape-shifting microswimmers

Journal Article · Mon Dec 02 00:00:00 EST 2019 · Physical Review Research · OSTI ID:1370836

Dou, Yong; Bishop, Kyle J. M.

Designing Synthetic Microcapsules That Undergo Biomimetic Communication and Autonomous Motion

Journal Article · Fri Aug 21 00:00:00 EDT 2015 · Langmuir · OSTI ID:1370836

Yashin, Victor V.; Kolmakov, German V.; Shum, Henry; +1 more

Active particles in complex and crowded environments

Journal Article · Wed Nov 23 00:00:00 EST 2016 · Reviews of Modern Physics · OSTI ID:1370836

Bechinger, Clemens; Di Leonardo, Roberto; Löwen, Hartmut; +3 more

Related Subjects

42 ENGINEERING
catalysis (homogeneous)
solar (photovoltaic)
bio-inspired
charge transport
mesostructured materials
materials and chemistry by design
synthesis (novel materials)
synthesis (self-assembly)

Title: Computational design of microscopic swimmers and capsules: From directed motion to collective behavior

Citation Formats

References (78)

Similar Records

Related Subjects