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Title: Inter-Individual Variability in Human Response to Low-Dose Ionizing Radiation, Final Report

In order to investigate inter-individual variability in response to low-dose ionizing radiation, we are working with three models, 1) in-vivo irradiated human skin, for which we have a realistic model, but with few subjects, all from a previous project, 2) ex-vivo irradiated human skin, for which we also have a realistic model, though with the limitations involved in keeping skin pieces alive in media, and 3) MatTek EpiDermFT skin plugs, which provides a more realistic model than cell lines, which is more controllable than human samples.
Authors:
 [1]
  1. Univ. of California, Davis, CA (United States)
Publication Date:
OSTI Identifier:
1308445
Report Number(s):
DOE DE--SC0001099
TRN: US1601817
DOE Contract Number:
SC0001099
Resource Type:
Technical Report
Research Org:
Univ. of California, Davis, CA (United States)
Sponsoring Org:
USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23)
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; LOW DOSE IRRADIATION; MAN; SKIN; IONIZING RADIATIONS; VARIATIONS; IN VIVO; EARLY RADIATION EFFECTS