Chip-based device for parallel sorting, amplification, detection, and identification of nucleic acid subsequences
Patent
·
OSTI ID:1289941
An apparatus for chip-based sorting, amplification, detection, and identification of a sample having a planar substrate. The planar substrate is divided into cells. The cells are arranged on the planar substrate in rows and columns. Electrodes are located in the cells. A micro-reactor maker produces micro-reactors containing the sample. The micro-reactor maker is positioned to deliver the micro-reactors to the planar substrate. A microprocessor is connected to the electrodes for manipulating the micro-reactors on the planar substrate. A detector is positioned to interrogate the sample contained in the micro-reactors.
- Research Organization:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC52-07NA27344
- Assignee:
- Lawrence Livermore National Security, LLC (Livermore, CA)
- Patent Number(s):
- 9,409,177
- Application Number:
- 12/401,714
- OSTI ID:
- 1289941
- Resource Relation:
- Patent File Date: 2009 Mar 11
- Country of Publication:
- United States
- Language:
- English
Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
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patent-application | July 2008 |
Droplet-based chemistry on a programmable micro-chip
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journal | January 2004 |
Dielectrophoresis-based programmable fluidic processors
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