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Title: High resolution pipette

A pipette includes a movable piston and a diaphragm that at least partly defines a fluid chamber enclosing a volume of working fluid. The piston displaces a volumetric amount of the working fluid in the chamber when moved. In response, the diaphragm displaces a smaller volumetric amount of fluid outside the chamber. A deamplification ratio is defined by the ratio of the volume displaced by the diaphragm to the volume displaced by the piston. The deamplification ratio is adjustable by adjusting or changing the diaphragm and/or by adjusting the size of the fluid chamber. The deamplifying pipette enables measuring and dispensing of very small volumes of liquid and is easily adapted to commercially available pipette components. Pipette components such as a pipette tip or adaptor may include a diaphragm to enable deamplification of the nominal volume capacity of a given pipette device.
Authors:
;
Publication Date:
OSTI Identifier:
1256015
Report Number(s):
9,358,538
13/873,962
DOE Contract Number:
SC0004927
Resource Type:
Patent
Resource Relation:
Patent File Date: 2013 Apr 30
Research Org:
The Regents of the University of Michigan, Ann Arbor, MI (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
99 GENERAL AND MISCELLANEOUS; 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY