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Title: Use of Galerina marginata genes and proteins for peptide production

The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in mushrooms. In particular, the present invention relates to using genes and proteins from Galerina species encoding peptides specifically relating to amatoxins in addition to proteins involved with processing cyclic peptide toxins. In a preferred embodiment, the present invention also relates to methods for making small peptides and small cyclic peptides including peptides similar to amanitin. Further, the present inventions relate to providing kits for making small peptides.
Authors:
; ; ;
Publication Date:
OSTI Identifier:
1241031
Report Number(s):
9,273,100
13/362,561
DOE Contract Number:
FG02-91ER20021
Resource Type:
Patent
Resource Relation:
Patent File Date: 2012 Jan 31
Research Org:
Board of Trustees of Michigan State University, East Lansing, MI (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 54 ENVIRONMENTAL SCIENCES