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Title: Structure-based design of potent HIV-1 protease inhibitors with modified P1-biphenyl ligands: Synthesis, biological evaluation, and enzyme–inhibitor X-ray structural studies

Authors:
 [1] ;  [1] ;  [1] ;  [2] ;  [2] ;  [3] ;  [2] ;  [4]
  1. Purdue Univ., West Lafayette, IN (United States)
  2. Georgia State Univ., Atlanta, GA (United States)
  3. Kumamoto Univ. Graduate School of Medicine and Pharmaceutical Sciences, Kumamoto (Japan)
  4. Kumamoto Univ. Graduate School of Medicine and Pharmaceutical Sciences, Kumamoto (Japan); National Institutes of Health, Bethesda, MD (United States); National Center for Global Health and Medicine, Tokyo (Japan)
Publication Date:
OSTI Identifier:
1214856
Resource Type:
Journal Article
Resource Relation:
Journal Name: Journal of Medicinal Chemistry; Journal Volume: 58; Journal Issue: 13
Research Org:
Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
Sponsoring Org:
NIH
Country of Publication:
United States
Language:
ENGLISH