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Title: Simplified one-pot synthesis of [.sup.18F]SFB for radiolabeling

A non-aqueous single pot synthesis of [.sup.18F]SFB is set forth. The [.sup.18F]SFB produced with this method is then used, for example, to label a peptide or an engineered antibody fragment (diabody) targeting human epidermal growth factor receptor 2 (HER2) as representative examples of labeled compounds for use as an injectable composition to locate abnormal tissue, specifically tumors within an animal or human using a PET scan.
Authors:
;
Publication Date:
OSTI Identifier:
1207285
Report Number(s):
9,096,647
13/924,397
DOE Contract Number:
FG02-06ER64249
Resource Type:
Patent
Resource Relation:
Patent File Date: 2013 Jun 21
Research Org:
The Regents Of The University Of California, Oakland, CA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE