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Title: Nucleic acid encoding a self-assembling split-fluorescent protein system

Patent ·
OSTI ID:1193372
;

The invention provides a protein labeling and detection system based on self-complementing fragments of fluorescent and chromophoric proteins. The system of the invention is exemplified with various combinations of self-complementing fragments derived from Aequorea victoria Green Fluorescent Protein (GFP), which are used to detect and quantify protein solubility in multiple assay formats, both in vitro and in vivo.

Research Organization:
Los Alamos National Security, LLC, Los Alamos, NM (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-98ER62647
Assignee:
Los Alamos National Security, LLC (Los Alamos, NM)
Patent Number(s):
9,081,014
Application Number:
14/166,770
OSTI ID:
1193372
Resource Relation:
Patent File Date: 2014 Jan 28
Country of Publication:
United States
Language:
English

References (42)

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