Drug Resistance Conferred by Mutations Outside the Active Site through Alterations in the Dynamic and Structural Ensemble of HIV-1 Protease
- UMASS, MED
- Research Organization:
- Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
- Sponsoring Organization:
- National Institutes of Health (NIH)
- OSTI ID:
- 1191714
- Journal Information:
- J. Am. Chem. Soc., Vol. 136, Issue (34) ; 08, 2014
- Country of Publication:
- United States
- Language:
- ENGLISH
Similar Records
Revertant mutation V48G alters conformational dynamics of highly drug resistant HIV protease PRS17
Revertant mutation V48G alters conformational dynamics of highly drug resistant HIV protease PRS17
Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics
Journal Article
·
Mon Nov 01 00:00:00 EDT 2021
· J. Mol. Graph. Model.
·
OSTI ID:1191714
+2 more
Revertant mutation V48G alters conformational dynamics of highly drug resistant HIV protease PRS17
Journal Article
·
Wed Aug 11 00:00:00 EDT 2021
· Journal of Molecular Graphics and Modelling
·
OSTI ID:1191714
+2 more
Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics
Journal Article
·
Fri Dec 16 00:00:00 EST 2016
· PLoS ONE
·
OSTI ID:1191714
+3 more