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Title: Inhibiting the Function of an Enzyme

In order to stop bacteria from reproducing and causing a disease like tuberculosis, researchers must first block its enzymes' ability to bind with certain molecules. A research team from Brandeis University worked with the Advanced Protein Characterization Facility at Argonne National Laboratory to define 13 different bacterial structures and uncover the mechanism by which their enzymes form and break bonds with molecules. This animation depicts how an enzyme may be inhibited using this knowledge.
Publication Date:
OSTI Identifier:
1188671
Resource Type:
Multimedia
Research Org:
ANL (Argonne National Laboratory (ANL), Argonne, IL (United States))
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; ENZYME; PATHOGEN; COFACTOR; SUBSTRATE; PATHOGEN REPRODUCTION; BOND