Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation

Adhikary, Ramkrishna; Yu, Wayne; Oda, Masayuki; Walker, Ross C.; Chen, Tingjian; Stanfield, Robyn L.; Wilson, Ian A.; Zimmermann, Jörg; Romesberg, Floyd E.

doi:10.1021/bi501417q

Title: Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation

Journal Article · Tue Mar 24 00:00:00 EDT 2015 · Biochemistry-US

DOI:https://doi.org/10.1021/bi501417q· OSTI ID:1182310

Adhikary, Ramkrishna; Yu, Wayne; Oda, Masayuki; Walker, Ross C.; Chen, Tingjian; Stanfield, Robyn L.; Wilson, Ian A.; Zimmermann, Jörg; Romesberg, Floyd E. ^[1]

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Research Organization:: Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: NIHNIAID

OSTI ID:: 1182310

Journal Information:: Biochemistry-US, Vol. 54, Issue (11) ; 03, 2015

Country of Publication:: United States

Language:: ENGLISH

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Cited by: 28 works

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Cited By (3)

Repertoire Analysis of Antibody CDR-H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification Jeliazkov, Jeliazko R.; Sljoka, Adnan; Kuroda, Daisuke Frontiers in Immunology, Vol. 9 https://doi.org/10.3389/fimmu.2018.00413	journal	March 2018
Deciphering evolution of immune recognition in antibodies Kaur, Harmeet; Sain, Neetu; Mohanty, Debasisa BMC Structural Biology, Vol. 18, Issue 1 https://doi.org/10.1186/s12900-018-0096-1	journal	December 2018
Characterizing the Diversity of the CDR-H3 Loop Conformational Ensembles in Relationship to Antibody Binding Properties Fernández-Quintero, Monica L.; Loeffler, Johannes R.; Kraml, Johannes Frontiers in Immunology, Vol. 9 https://doi.org/10.3389/fimmu.2018.03065	journal	January 2019

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