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Title: Hydrolysis of DFP and the Nerve Agent ( S )-Sarin by DFPase Proceeds along Two Different Reaction Pathways: Implications for Engineering Bioscavengers

Authors:
 [1] ;  [2] ;  [3] ;  [1] ;  [4]
  1. UT/ORNL Center for Molecular Biophysics, Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6309, United States, Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee 37996, United States
  2. Institut de Biologie Structurale “Jean-Pierre Ebel”, 41 rue Jules Horowitz, 38027 Grenoble Cedex 1, France
  3. Center for Structural and Molecular Biology, Biology and Soft Matter Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6309, United States
  4. UT/ORNL Center for Molecular Biophysics, Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6309, United States
Publication Date:
OSTI Identifier:
1177836
Grant/Contract Number:
AC05-00OR22752
Type:
Published Article
Journal Name:
Journal of Physical Chemistry. B, Condensed Matter, Materials, Surfaces, Interfaces and Biophysical Chemistry
Additional Journal Information:
Journal Volume: 118; Journal Issue: 17; Related Information: CHORUS Timestamp: 2017-11-14 13:56:49; Journal ID: ISSN 1520-6106
Publisher:
American Chemical Society
Sponsoring Org:
USDOE National Nuclear Security Administration (NNSA)
Country of Publication:
United States
Language:
English