Human AZU-1 gene, variants thereof and expressed gene products
A human AZU-1 gene, mutants, variants and fragments thereof. Protein products encoded by the AZU-1 gene and homologs encoded by the variants of AZU-1 gene acting as tumor suppressors or markers of malignancy progression and tumorigenicity reversion. Identification, isolation and characterization of AZU-1 and AZU-2 genes localized to a tumor suppressive locus at chromosome 10q26, highly expressed in nonmalignant and premalignant cells derived from a human breast tumor progression model. A recombinant full length protein sequences encoded by the AZU-1 gene and nucleotide sequences of AZU-1 and AZU-2 genes and variant and fragments thereof. Monoclonal or polyclonal antibodies specific to AZU-1, AZU-2 encoded protein and to AZU-1, or AZU-2 encoded protein homologs.
- Research Organization:
- Univ. of California, Oakland, CA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC03-76SF00098
- Assignee:
- University Of California, The Regents Of
- Patent Number(s):
- 6,753,154
- Application Number:
- 09/344,624
- OSTI ID:
- 1174911
- Country of Publication:
- United States
- Language:
- English
AZU-1: A Candidate Breast Tumor Suppressor and Biomarker for Tumor Progression
|
journal | April 2000 |
Similar Records
AZU-1:a candidate breast tumor suppressor and biomarker for tumor progression
p53 Mutational status and survival of human breast cancer MCF-7 cell variants after exposure to X rays or fission neutrons