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Title: Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display

The invention provides multifunctional fusion constructs which are rapidly incorporated into a macromolecular structure such as a phycobilisome such that the fusion proteins are separated from one another and unable to self-associate. The invention provides methods and compositions for displaying a functional polypeptide domain on an oligomeric phycobiliprotein, including fusion proteins comprising a functional displayed domain and a functional phycobiliprotein domain incorporated in a functional oligomeric phycobiliprotein. The fusion proteins provide novel specific labeling reagents.
Authors:
;
Publication Date:
OSTI Identifier:
1174586
Report Number(s):
6,649,376
09/469,194
DOE Contract Number:
FG-91ER61125
Resource Type:
Patent
Research Org:
The Regents of the University of California, Oakland, CA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES