Pathogen Virulence Factors: Unique Probes of Plant Cell Structure and Function (Final Technical Report)
- Univ. of North Carolina, Chapel Hill, NC (United States)
Our long term aim over our many years of generous DOE-BES funding was to understand mechanisms by which the pathogen virulence factors (called ‘type III effectors’) AvrRpm1 and AvrB activate the plant NLR immune receptor RPM1. In general effectors are delivered from the infecting bacteria into host cells by the type III pilus, where they manipulate host machinery to help pathogens overcome host defense. Delivery of effectors to increase virulence is a general feature of all classes of plant pathogens, from fungi to insects to oomcyetes and bacteria. Hence, understanding the overall diversity of effectors, their myriad delivery systems and their effectors on host cell biology, is of central importance in plant immunology.
- Research Organization:
- Univ. of North Carolina, Chapel Hill, NC (United States)
- Sponsoring Organization:
- USDOE-Office of Science (SC) Basic Energy Sciences (BES)
- DOE Contract Number:
- FG02-95ER20187
- OSTI ID:
- 1171465
- Report Number(s):
- DOE-FG02-95ER20187
- Country of Publication:
- United States
- Language:
- English
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