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Title: Metal ion and ligand binding of integrin [alpha subscript 5 beta subscript 1]

Journal Article · · Proc. Natl. Acad. Sci. USA
;  [1]
  1. BCH
+ Show Author Affiliations

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
National Institutes of Health (NIH)
OSTI ID:
1168483
Journal Information:
Proc. Natl. Acad. Sci. USA, Vol. 111, Issue (50) ; 12, 2014
Country of Publication:
United States
Language:
ENGLISH
Citation Metrics:
Cited by: 60 works
Citation information provided by
Web of Science

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Role of ADMIDAS Cation-binding Site in Ligand Recognition by Integrin α 5 β 1 journal October 2003
Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces journal December 2008
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Analysis of protein-ligand interactions by fluorescence polarization journal March 2011
Structure-Guided Design of a High-Affinity Platelet Integrin  IIb 3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS journal March 2012
The Role of the CPNKEKEC Sequence in the β 2 Subunit I Domain in Regulation of Integrin α L β 2 (LFA-1) journal March 2002
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Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants journal December 1993
An internal ligand-bound, metastable state of a leukocyte integrin, α X β 2 journal November 2013
The Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin β 2 Subunit at 1.8-Å Resolution journal June 2005
Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics journal September 2004
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Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation journal February 2021
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Structural basis for selectin mechanochemistry journal December 2008
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Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening journal December 2010
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Cited By (16)

Integrin Activation: Implications for Axon Regeneration journal March 2018
Targeting the Tie2–αvβ3 integrin axis with bi-specific reagents for the inhibition of angiogenesis journal August 2018
Integrin β1 is bound to galectin-1 in human trophoblast journal September 2017
Conformational equilibria and intrinsic affinities define integrin activation journal January 2017
High Affinity vs. Native Fibronectin in the Modulation of αvβ3 Integrin Conformational Dynamics: Insights from Computational Analyses and Implications for Molecular Design journal January 2017
Fusion surface structure, function, and dynamics of gamete fusogen HAP2 journal October 2018
Regulation of Plasma Membrane Localization of the Na+-taurocholate cotransporting polypeptide (Ntcp) by Hyperosmolarity and Tauroursodeoxycholate journal December 2015
Investigating the Interaction of Cyclic RGD Peptidomimetics with αVβ6 Integrin by Biochemical and Molecular Docking Studies journal September 2017
Mechanistic basis for the recognition of laminin-511 by α6β1 integrin journal September 2017
Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin journal January 2016
Regulation of Plasma Membrane Localization of the Na+-Taurocholate Cotransporting Polypeptide (Ntcp) by Hyperosmolarity and Tauroursodeoxycholate journal October 2015
Relating conformation to function in integrin α 5 β 1 journal June 2016
Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats journal August 2016
A systematic survey of conformational states in β1 and β4 integrins using negative-stain electron microscopy journal April 2018
Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer journal September 2017
Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin text January 2016

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