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Title: Pnp gene modification for improved xylose utilization in Zymomonas

The endogenous pnp gene encoding polynucleotide phosphorylase in the Zymomonas genome was identified as a target for modification to provide improved xylose utilizing cells for ethanol production. The cells are in addition genetically modified to have increased expression of ribose-5-phosphate isomerase (RPI) activity, as compared to cells without this genetic modification, and are not limited in xylose isomerase activity in the absence of the pnp modification.
Authors:
; ; ; ;
Publication Date:
OSTI Identifier:
1165440
Report Number(s):
8,911,983
13/711,646
DOE Contract Number:
FC36-07GO17056
Resource Type:
Patent
Research Org:
E I Du Pont de Nemours and Company, Wilmington, DE (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 09 BIOMASS FUELS