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Title: Amphiphiles for protein solubilization and stabilization

The invention provides amphiphiles for manipulating membrane proteins. The amphiphiles can feature carbohydrate-derived hydrophilic groups and branchpoints in the hydrophilic moiety and/or in a lipophilic moiety. Such amphiphiles are useful as detergents for solubilization and stabilization of membrane proteins, including photosynthetic protein superassemblies obtained from bacterial membranes.
Authors:
; ; ;
Publication Date:
OSTI Identifier:
1163212
Report Number(s):
8,877,906
13/608,385
DOE Contract Number:
W-31-109-ENG38
Resource Type:
Patent
Research Org:
Wisconsin Aumni Research Foundation, Madison, WI (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES