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Title: Image-Guided Synthesis Reveals Potent Blood-Brain Barrier Permeable Histone Deacetylase Inhibitors

Authors:
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Publication Date:
OSTI Identifier:
1160043
Report Number(s):
BNL--106124-2014-JA
R&D Project: MO-085; KP1602010
DOE Contract Number:
DE-AC02-98CH10886
Resource Type:
Journal Article
Resource Relation:
Journal Name: ACS CHEMICAL NEUROSCIENCE; Journal Volume: 5
Research Org:
Brookhaven National Laboratory (BNL) Positron Emission Tomography (PET) Facility
Sponsoring Org:
USDOE SC OFFICE OF BIOLOGICAL & ENVIRONMENTAL RESEARCH
Country of Publication:
United States
Language:
English
Subject:
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY histone acetylase; PET (positron emission tomography); BBB (blood-brain barrier); CNS (central nervous system); C11 (carbon-11); brain diseases; blood-brain barrier permeability; benzamides; HDAC (histone deacetylase); positron emission tomography (PET) facility