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Title: Plume collimation for laser ablation electrospray ionization mass spectrometry

In various embodiments, a device may generally comprise a capillary having a first end and a second end; a laser to emit energy at a sample in the capillary to ablate the sample and generate an ablation plume in the capillary; an electrospray apparatus to generate an electrospray plume to intercept the ablation plume to produce ions; and a mass spectrometer having an ion transfer inlet to capture the ions. The ablation plume may comprise a collimated ablation plume. The device may comprise a flow cytometer. Methods of making and using the same are also described.
Authors:
;
Publication Date:
OSTI Identifier:
1157080
Report Number(s):
8,829,426
13/549,988
DOE Contract Number:
FG02-01ER15129
Resource Type:
Patent
Research Org:
The George Washington University, Washington, DC (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION