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Title: Radio-methyl vorozole and methods for making and using the same

Radiotracer vorozole compounds for in vivo and in vitro assaying, studying and imaging cytochrome P450 aromatase enzymes in humans, animals, and tissues and methods for making and using the same are provided. [N-radio-methyl] vorozole substantially separated from an N-3 radio-methyl isomer of vorozole is provided. Separation is accomplished through use of chromatography resins providing multiple mechanisms of selectivity.
Authors:
; ;
Publication Date:
OSTI Identifier:
1150092
Report Number(s):
8,802,053
13/847,136
DOE Contract Number:
AC02-98CH10886
Resource Type:
Patent
Research Org:
BNL (Brookhaven National Laboratory (BNL), Upton, NY (United States))
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY