skip to main content

SciTech ConnectSciTech Connect

Title: As if Biomarker Discovery Isn't Hard Enough: the Consequences of Poorly Characterized Reagents

The advent of high throughput omic technologies over the past two decades has driven a vast expansion in the search for clinical biomarkers, as manifested by the plethora of publications on biomarker discovery (over 8,600) listed on PubMed since 2000. Unfortunately, the same time period has seen a relative dearth of clinically validated biomarkers that have received FDA approval; only 10 new cancer biomarkers have been approved by the FDA in the same time period [1].
Authors:
Publication Date:
OSTI Identifier:
1130224
Report Number(s):
PNNL-SA-99249
DOE Contract Number:
AC05-76RL01830
Resource Type:
Journal Article
Resource Relation:
Journal Name: Clinical Chemistry, 60(1):290-291
Research Org:
Pacific Northwest National Laboratory (PNNL), Richland, WA (US)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
biomarker discovery; characterized reagents