Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel [mu]M Leads for the Development of nM BACE-1 ([beta]-Site APP Cleaving Enzyme 1) Inhibitors
- SPRI
- Research Organization:
- Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
- Sponsoring Organization:
- INDUSTRY
- OSTI ID:
- 1107403
- Journal Information:
- J. Med. Chem., Vol. 53, Issue (3) ; 02, 2010
- Country of Publication:
- United States
- Language:
- ENGLISH
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