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Title: Mass spectrometric immunoassay

Rapid mass spectrometric immunoassay methods for detecting and/or quantifying antibody and antigen analytes utilizing affinity capture to isolate the analytes and internal reference species (for quantification) followed by mass spectrometric analysis of the isolated analyte/internal reference species. Quantification is obtained by normalizing and calibrating obtained mass spectrum against the mass spectrum obtained for an antibody/antigen of known concentration.
Authors:
; ;
Publication Date:
OSTI Identifier:
1087876
Report Number(s):
8,486,713
13/421,633
DOE Contract Number:
FG02-91ER61127
Resource Type:
Patent
Research Org:
Intrinsic Bioprobes, Inc. (Tempe, AZ)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES