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Title: Simplified one-pot synthesis of [.sup.18F]SFB for radiolabeling

A non-aqueous single pot synthesis of [.sup.18F]SFB is set forth. The [.sup.18F]SFB produced with this method is then used, for example, to label a peptide or an engineered antibody fragment (diabody) targeting human epidermal growth factor receptor 2 (HER2) as representative examples of labeled compounds for use as an injectable composition to locate abnormal tissue, specifically tumors within an animal or human using a PET scan.
Authors:
;
Publication Date:
OSTI Identifier:
1087870
Report Number(s):
8,487,077
13/063,741
DOE Contract Number:
FG02-06ER64249
Resource Type:
Patent
Research Org:
The Regents Of The University Of California (Oakland, CA)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE