A Lattice Boltzmann Fictitious Domain Method for Modeling Red Blood Cell Deformation and Multiple-Cell Hydrodynamic Interactions in Flow

Journal Article · Sat Jul 20 00:00:00 EDT 2013 · International Journal for Numerical Methods in Fluids, 72(8):895-911

DOI:https://doi.org/10.1002/fld.3764· OSTI ID:1083399

Shi, Xing; Lin, Guang; Zou, Jianfeng; Fedosov, Dmitry A.

To model red blood cell (RBC) deformation in flow, the recently developed LBM-DLM/FD method ([Shi and Lim, 2007)29], derived from the lattice Boltzmann method and the distributed Lagrange multiplier/fictitious domain methodthe fictitious domain method, is extended to employ the mesoscopic network model for simulations of red blood cell deformation. The flow is simulated by the lattice Boltzmann method with an external force, while the network model is used for modeling red blood cell deformation and the fluid-RBC interaction is enforced by the Lagrange multiplier. To validate parameters of the RBC network model, sThe stretching numerical tests on both coarse and fine meshes are performed and compared with the corresponding experimental data to validate the parameters of the RBC network model. In addition, RBC deformation in pipe flow and in shear flow is simulated, revealing the capacity of the current method for modeling RBC deformation in various flows.

• Research Organization: Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
• Sponsoring Organization: USDOE
• DOE Contract Number: AC05-76RL01830
• OSTI ID: 1083399
• Report Number(s): PNNL-SA-78506; KJ0401000
• Journal Information: International Journal for Numerical Methods in Fluids, 72(8):895-911, Journal Name: International Journal for Numerical Methods in Fluids, 72(8):895-911
• Country of Publication: United States
• Language: English