Complete Genome Sequence of a thermotolerant sporogenic lactic acid bacterium, Bacillus coagulans strain 36D1

Journal Article · Sat Jan 01 00:00:00 EST 2011 · Standards in Genomic Sciences

DOI:https://doi.org/10.4056/sigs.2365342· OSTI ID:1049879

Rhee, Mun Su ^[1]; Moritz, Brelan E ^[1]; Xie, Gary ^[2]; Glavina Del Rio, Tijana ^[3]; Dalin, Eileen ^[3]; Tice, Hope ^[3]; Bruce, David ^[2]; Goodwin, Lynne A ^[2]; Chertkov, Olga ^[2]; Brettin, Thomas S ^[4]; Han, Cliff ^[2]; Detter, J Chris ^[3]; Pitluck, Sam ^[3]; Land, Miriam L ^[4]; Patel, Milind ^[1]; Ou, Mark ^[1]; Harbrucker, Roberta ^[1]; Ingram, Lonnie O ^[5]; Shanmugam, Keelnathan T ^[5]

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1. University of Florida, Gainesville
2. Los Alamos National Laboratory (LANL)
3. U.S. Department of Energy, Joint Genome Institute
4. ORNL
5. University of Florida

Bacillus coagulans is a ubiquitous soil bacterium that grows at 50-55 C and pH 5.0 and fer- ments various sugars that constitute plant biomass to L (+)-lactic acid. The ability of this spo- rogenic lactic acid bacterium to grow at 50-55 C and pH 5.0 makes this organism an attrac- tive microbial biocatalyst for production of optically pure lactic acid at industrial scale not only from glucose derived from cellulose but also from xylose, a major constituent of hemi- cellulose. This bacterium is also considered as a potential probiotic. Complete genome se- quence of a representative strain, B. coagulans strain 36D1, is presented and discussed.

• Research Organization: Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
• Sponsoring Organization: Work for Others (WFO)
• DOE Contract Number: DE-AC05-00OR22725
• OSTI ID: 1049879
• Journal Information: Standards in Genomic Sciences, Vol. 5, Issue 3; ISSN 1944-3277
• Country of Publication: United States
• Language: English

Related Subjects

09 BIOMASS FUELS
BACILLUS
BIOMASS
CELLULOSE
GLUCOSE
LACTIC ACID
PRODUCTION
SACCHARIDES
SOILS
STRAINS
XYLOSE
Bacillus coagulans
genome sequence
lactic acid
fermentation
probiotics
ther- motolerant bacterium