Integrated MOSFET-Embedded-Cantilever-Based Biosensor Characteristic for Detection of Anthrax Simulant

Journal Article · Sat Jan 01 00:00:00 EST 2011 · IEEE Electron Device Letters

DOI:https://doi.org/10.1109/LED.2010.2098015· OSTI ID:1041096

Mostafa, Salwa ^[1]; Lee, Ida ^[2]; Islam, Syed K ^[1]; Eliza, Sazia A. ^[1]; Shekhawat, Gajendra ^[3]; Dravid, Vinayak ^[3]; Tulip, Fahmida S ^[2]

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1. University of Tennessee, Knoxville (UTK)
2. ORNL
3. Northwestern University, Evanston

In this work, MOSFET-embedded cantilevers are configured as microbial sensors for detection of anthrax simulants, Bacillus thuringiensis. Anthrax simulants attached to the chemically treated gold-coated cantilever cause changes in the MOSFET drain current due to the bending of the cantilever which indicates the detection of anthrax simulant. Electrical properties of the anthrax simulant are also responsible for the change in the drain current. The test results suggest a detection range of 10 L of stimulant test solution (a suspension population of 1.3 107 colony-forming units/mL diluted in 40% ethanol and 60% deionized water) with a linear response of 31 A/ L.

• Research Organization: Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
• Sponsoring Organization: USDOE Office of Science (SC)
• DOE Contract Number: DE-AC05-00OR22725
• OSTI ID: 1041096
• Journal Information: IEEE Electron Device Letters, Vol. 32, Issue 3; ISSN 0741-3106
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
60 APPLIED LIFE SCIENCES
BACILLUS
BENDING
DETECTION
ELECTRICAL PROPERTIES
ETHANOL
MOSFET
SENSORS
WATER