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Title: Quality Enhancement and Nerve Fibre Layer Artefacts Removal in Retina Fundus Images by Off Axis Imaging

Retinal fundus images acquired with non-mydriatic digital fundus cameras are a versatile tool for the diagnosis of various retinal diseases. Because of the ease of use of newer camera models and their relative low cost, these cameras are employed worldwide by retina specialists to diagnose diabetic retinopathy and other degenerative diseases. Even with relative ease of use, the images produced by these systems sometimes suffer from reflectance artefacts mainly due to the nerve fibre layer (NFL) or other camera lens related reflections. We propose a technique that employs multiple fundus images acquired from the same patient to obtain a single higher quality image without these reflectance artefacts. The removal of bright artefacts, and particularly of NFL reflectance, can have great benefits for the reduction of false positives in the detection of retinal lesions such as exudate, drusens and cotton wool spots by automatic systems or manual inspection. If enough redundant information is provided by the multiple images, this technique also compensates for a suboptimal illumination. The fundus images are acquired in straightforward but unorthodox manner, i.e. the stare point of the patient is changed between each shot but the camera is kept fixed. Between each shot, the apparent shape andmore » position of all the retinal structures that do not exhibit isotropic reflectance (e.g. bright artefacts) change. This physical effect is exploited by our algorithm in order to extract the pixels belonging to the inner layers of the retina, hence obtaining a single artefacts-free image.« less
Authors:
 [1] ;  [1] ;  [1] ;  [2] ;  [1] ;  [2]
  1. ORNL
  2. University of Tennessee, Knoxville (UTK)
Publication Date:
OSTI Identifier:
1038784
DOE Contract Number:
DE-AC05-00OR22725
Resource Type:
Conference
Resource Relation:
Conference: ICIP 2011: 2011 IEEE International Conference on Image Processing, Brussels, Belgium, 20110911, 20110911
Research Org:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Org:
USDOE; Work for Others (WFO)
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES; ALGORITHMS; CAMERAS; DETECTION; DIAGNOSIS; DIAGNOSTIC TECHNIQUES; SENSE ORGANS DISEASES; ILLUMINANCE; IMAGE PROCESSING; NERVES; PATIENTS; REMOVAL; RETINA; SHAPE