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Title: Imidazo[2,1-b]thiazoles: Multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases

The design and enzyme activities of a novel class of imidazo[2,1-b]thiazoles is presented.
Authors:
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ;  [1]
  1. (Abbott)
Publication Date:
OSTI Identifier:
1025625
Resource Type:
Journal Article
Resource Relation:
Journal Name: Bioorg. Med. Chem. Lett.; Journal Volume: 20; Journal Issue: (8) ; 04, 2010
Research Org:
Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
Sponsoring Org:
INDUSTRY
Country of Publication:
United States
Language:
ENGLISH
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES; DESIGN; ENZYMES; GROWTH FACTORS; PHOSPHOTRANSFERASES; THIAZOLES; TYROSINE