A Three-way Comparative Genomic Analysis of Mannheimia haemolytica Isolates

Journal Article · Mon Oct 04 00:00:00 EDT 2010 · BMC Genomics, 11:535

DOI:https://doi.org/10.1186/1471-2164-11-535· OSTI ID:1001109

Lawrence, Paulraj; Kittichotirat, Weerayuth; McDermott, Jason E; Bumgarner, Roger E

Mannhemia haemolytica is a Gram- negative bacterium and the principal etiological agent associated with bovine respiratory disease complex. They transform from a benign commensal to a deadly pathogen during stress such as viral infection and transportation to feedlots, and cause acute pleuropneumonia commonly known as shipping fever. The U.S beef industry alone loses more than one billion dollars annually to shipping fever and despite its enormous economic importance there are no specific and accurate genetic markers, which would aid in understanding M. haemolytica pathogenesis and epidemiology at molecular level and assist in devising an effective control strategy.

• Research Organization: Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
• Sponsoring Organization: USDOE
• DOE Contract Number: AC05-76RL01830
• OSTI ID: 1001109
• Report Number(s): PNNL-SA-75660; 400412000; TRN: US201101%%843
• Journal Information: BMC Genomics, 11:535, Vol. 11; ISSN 1471-2164
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
60 APPLIED LIFE SCIENCES
99 GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE
CATTLE
DISEASES
DOLLARS
ECONOMICS
EPIDEMIOLOGY
FEVER
GENETICS
MEAT
PATHOGENESIS
PATHOGENS