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Title: HIV vaccine enters human efficacy trials

Abstract

The HIV mosaic vaccine was originally designed at Los Alamos National Laboratory using a machine learning algorithm designed by Bette Korber and her team. It's the first computationally designed HIV vaccine. Through a decade of testing, it has shown promise and is now in human efficacy trials. The study will evaluate whether the investigational vaccine regimen is safe and able to reduce the incidence of HIV infection among 2,600 sexually active women in sub-Saharan Africa. The new study, HVTN 705/HPX2008, is known as “Imbokodo,” the Zulu word for “rock,” from a South African saying that refers to the strength of women and their importance in the community.

Authors:
Publication Date:
Research Org.:
LANL (Los Alamos National Laboratory (LANL), Los Alamos, NM (United States))
Sponsoring Org.:
USDOE National Nuclear Security Administration (NNSA)
OSTI Identifier:
1487129
Resource Type:
Multimedia
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; HIV MOSAIC VACCINE; IMBOKODO; TRANSMISSIBLE DISEASE; MACHINE LEARNING; HIV GENOME DATABASE; COMPUTER-GENERATED VACCINE SEQUENCE

Citation Formats

Korber, Bette. HIV vaccine enters human efficacy trials. United States: N. p., 2018. Web.
Korber, Bette. HIV vaccine enters human efficacy trials. United States.
Korber, Bette. Fri . "HIV vaccine enters human efficacy trials". United States. https://www.osti.gov/servlets/purl/1487129.
@article{osti_1487129,
title = {HIV vaccine enters human efficacy trials},
author = {Korber, Bette},
abstractNote = {The HIV mosaic vaccine was originally designed at Los Alamos National Laboratory using a machine learning algorithm designed by Bette Korber and her team. It's the first computationally designed HIV vaccine. Through a decade of testing, it has shown promise and is now in human efficacy trials. The study will evaluate whether the investigational vaccine regimen is safe and able to reduce the incidence of HIV infection among 2,600 sexually active women in sub-Saharan Africa. The new study, HVTN 705/HPX2008, is known as “Imbokodo,” the Zulu word for “rock,” from a South African saying that refers to the strength of women and their importance in the community.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2018},
month = {10}
}

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