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Title: Supercomputer Simulations Help Develop New Approach to Fight Antibiotic Resistance

ORNL leveraged powerful supercomputing to support research led by University of Oklahoma scientists to identify chemicals that seek out and disrupt bacterial proteins called efflux pumps, known to be more »a major cause of antibiotic resistance. By running simulations on Titan, the team selected molecules most likely to target and potentially disable the assembly of efflux pumps found in E. coli bacteria cells.« less
Title: Supercomputer Simulations Help Develop New Approach to Fight Antibiotic Resistance
Authors:
Publication Date: 2016-11-17
OSTI Identifier: 1332726
Resource Type: Multimedia
Research Org: ORNL (Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States))
Sponsoring Org: USDOE
Subject: 47 OTHER INSTRUMENTATION ; ANTIBIOTIC RESISTANCE ; BACTERIAL PROTEINS ; FUNGI ; VIRUSES ; EFFLUX PUMPS ; SUPERCOMPUTERS
Country of Publication: United States
Language: English
Run Time:
System Entry Date: 2016-11-23