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Title: Biomedical Imaging with Partially Coherent, Laser-Driven Plasma X-Ray Sources

Ultrafast, high-intensity laser pulses incident upon condensed matter targets are used to generate high-density plasmas that emit x-ray pulses with sub-picosecond temporal length and significant transmore »verse coherence. The short pulse length has been exploited for ultrafast dynamics measurements of solvated transition metal complexes by XAFS spectroscopy. The high transverse coherence of the x-rays has been used for in-line holographic hard x-ray imaging of biomedical materials and tissues. This imaging method is more than a thousand times more sensitive to density variations of tissues than conventional absorption methods and enables imaging of soft tissues with high contrast without the use of contrast agents. The presentation will discuss the principles of the technique and its application to the imaging of murine livers with various tumors. The specific focus of this work rests on the imaging of the angiogenesis during the development of hepatocellular carcinoma and other cancers metastasizing in the liver.« less
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Title: Biomedical Imaging with Partially Coherent, Laser-Driven Plasma X-Ray Sources
Authors:
Publication Date: 2008-06-04
OSTI Identifier: 1122581
DOE Contract Number: ACO2-06CH11357
Resource Type: Multimedia
Resource Relation: Conference: APS Colloquium Series, Advanced Photon Source (APS) at Argonne National Laboratory, Argonne, Illinois (United States), presented on June 04, 2008
Research Org: ANL (Argonne National Laboratory (ANL), Argonne, IL (United States)); Advanced Photon Source (APS)
Sponsoring Org: USDOE Office of Science (SC)
Subject: 62 RADIOLOGY AND NUCLEAR MEDICINE
Country of Publication: United States
Language: English
Run Time: 0:51:13
System Entry Date: 2016-01-28