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Title: Blood Flow: Multi-scale Modeling and Visualization (July 2011)

Abstract

Multi-scale modeling of arterial blood flow can shed light on the interaction between events happening at micro- and meso-scales (i.e., adhesion of red blood cells to the arterial wall, clot formation) and at macro-scales (i.e., change in flow patterns due to the clot). Coupled numerical simulations of such multi-scale flow require state-of-the-art computers and algorithms, along with techniques for multi-scale visualizations. This animation presents early results of two studies used in the development of a multi-scale visualization methodology. The first illustrates a flow of healthy (red) and diseased (blue) blood cells with a Dissipative Particle Dynamics (DPD) method. Each blood cell is represented by a mesh, small spheres show a sub-set of particles representing the blood plasma, while instantaneous streamlines and slices represent the ensemble average velocity. In the second we investigate the process of thrombus (blood clot) formation, which may be responsible for the rupture of aneurysms, by concentrating on the platelet blood cells, observing as they aggregate on the wall of an aneruysm. Simulation was performed on Kraken at the National Institute for Computational Sciences. Visualization was produced using resources of the Argonne Leadership Computing Facility at Argonne National Laboratory.

Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States); Brown Univ., Providence, RI (United States)
Sponsoring Org.:
USDOE Office of Science (SC); National Science Foundation (NSF); Univ. of Tennessee, Knoxville, TN (United States). National Institute for Computational Sciences (NICS)
OSTI Identifier:
1045607
Resource Type:
Multimedia
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 97 MATHEMATICS AND COMPUTING; ANL; BROWN UNIVERSITY; BLOOD FLOW; MICRO AND MESO-SCALES; MULTI-SCALE MODELING AND VISUALIZATION; PLASMA; VELOCITY; DPD

Citation Formats

None. Blood Flow: Multi-scale Modeling and Visualization (July 2011). United States: N. p., 2011. Web.
None. Blood Flow: Multi-scale Modeling and Visualization (July 2011). United States.
None. Sat . "Blood Flow: Multi-scale Modeling and Visualization (July 2011)". United States. https://www.osti.gov/servlets/purl/1045607.
@article{osti_1045607,
title = {Blood Flow: Multi-scale Modeling and Visualization (July 2011)},
author = {None},
abstractNote = {Multi-scale modeling of arterial blood flow can shed light on the interaction between events happening at micro- and meso-scales (i.e., adhesion of red blood cells to the arterial wall, clot formation) and at macro-scales (i.e., change in flow patterns due to the clot). Coupled numerical simulations of such multi-scale flow require state-of-the-art computers and algorithms, along with techniques for multi-scale visualizations. This animation presents early results of two studies used in the development of a multi-scale visualization methodology. The first illustrates a flow of healthy (red) and diseased (blue) blood cells with a Dissipative Particle Dynamics (DPD) method. Each blood cell is represented by a mesh, small spheres show a sub-set of particles representing the blood plasma, while instantaneous streamlines and slices represent the ensemble average velocity. In the second we investigate the process of thrombus (blood clot) formation, which may be responsible for the rupture of aneurysms, by concentrating on the platelet blood cells, observing as they aggregate on the wall of an aneruysm. Simulation was performed on Kraken at the National Institute for Computational Sciences. Visualization was produced using resources of the Argonne Leadership Computing Facility at Argonne National Laboratory.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2011},
month = {1}
}

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