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Title: Evolution in a Contemporary Human Population: Intersexual Constraints and Costs of Reproduction

In this talk I will use an analysis of the population described in the Framingham Heart Study to make three points: (1) Contemporary humans are still evolving, and we can in part predict how they aremore » responding to selection. (2) Selection on males and females differs, and its interaction with intersexual genetic correlations constrains the responses of each sex to selection. In other words, males are constrained by processes occurring in females, and females are constrained by processes occurring in males. (3) There are costs of reproduction in humans that are paid in lifespan, but it is likely that these costs were deferred to a point at which our ancestors would already have died for other reasons. When we detect those costs today, we find evidence that the versions of some genes that make us susceptible to cancer also increase reproductive success early in life. This confirms in humans a central assumption of the evolutionary theory of aging – the existence of genes that mediate a tradeoff between reproduction and survival - that had previously only been confirmed in model organisms like fruit flies and worms.« less
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Title: Evolution in a Contemporary Human Population: Intersexual Constraints and Costs of Reproduction
Authors:
Publication Date: 2012-03-14
OSTI Identifier: 1043278
Resource Type: Multimedia
Resource Relation: Conference: Wednesday Colloquium Series, Princeton Plasma Physics Laboratory, Princeton, New Jersey, presented on March 14, 2012
Research Org: PPPL (Princeton Plasma Physics Laboratory (PPPL), Princeton, NJ (United States))
Sponsoring Org: USDOE Office of Science (SC)
Subject: 59 BASIC BIOLOGICAL SCIENCES ; Evolution
Country of Publication: United States
Language: English
Run Time:
System Entry Date: 2016-06-27