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Title: Nature's Nanomachines: The Physics of Biomolecular Motors

Molecular motors are tiny protein engines that use the chemical energy stored in a molecular bond to produce a variety of complex movements within biological cells. I will present an overview of thesemore » fascinating machines as well as the current technologies used to study them. One specific motor, RNA polymerase, transcribes DNA into messenger RNA, using the energy from nucleotide polymerization to move along a DNA template. Optical traps have been used to visualize these motions with ever increasing precision. I will present optical trapping data that provide evidence of a proofreading mechanism, i.e. a molecular backspace key, used by RNA polymerase to correct mistakes made in the RNA.« less
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Title: Nature's Nanomachines: The Physics of Biomolecular Motors
Authors:
Publication Date: 2004-10-13
OSTI Identifier: 1016833
DOE Contract Number: AC02-07CH11359
Other Number(s): TRN: US201207%%249
Resource Type: Multimedia
Resource Relation: Conference: Fermilab Colloquia, Fermi National Accelerator Laboratory (FNAL), Batvia, Illinois (United States), presented on October 13, 2004
Research Org: FNAL (Fermi National Accelerator Laboratory (FNAL), Batavia, IL (United States))
Sponsoring Org: USDOE Office of Science (SC)
Subject: 59 BASIC BIOLOGICAL SCIENCES ; 60 APPLIED LIFE SCIENCES ; ACCURACY ; DNA ; MESSENGER-RNA ; MOLECULAR STRUCTURE ; NUCLEOTIDES ; PHYSICS ; POLYMERIZATION ; PROTEINS ; RNA ; RNA POLYMERASES ; TRAPPING
Country of Publication: United States
Language: English
Run Time: 1:09:58
System Entry Date: 2016-01-28