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Title: From Atoms to Animals: The Vital Force in Biology

Abstract

Perhaps the most significant event in intellectual history has occurred over the past several decades, a convergence of the sciences, a blurring of the distinctions between disciplines, from physics to chemistry to biology. Fundamental questions about human existence have been answered in chemical terms. What brings matter to life? What are our origins? What is the basis of cognitive activity? These and related questions have been a fertile area for philosophy and nonscientific analysis. The long history of such alternative approaches persists to this day. Life chemistry is explained by protein catalysts, in their simplest form known as enzymes, and in their full complexity, referred to as molecular machines. An example of great significance is the so-called transcription machinery, which reads out the genetic code, to direct the formation and function of all living things. The atomic structure of the transcription machinery was determined at Stanford, with the use of intense X-ray beams and facilities at the Stanford Synchrotron Radiation Laboratory at SLAC. The result is an image of this complex machinery in action, bringing genetic information to life.

Authors:
 [1]
  1. Stanford Univ., CA (United States)
Publication Date:
Research Org.:
SLAC National Accelerator Lab., Menlo Park, CA (United States)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1014052
DOE Contract Number:
AC02-76SF00515
Resource Type:
Multimedia
Resource Relation:
Conference: SLAC Public Lecture Series, SLAC National Accelerator Laboratory, Menlo Park, California, presented on February 26, 2008
Country of Publication:
United States
Language:
English
Subject:
43 PARTICLE ACCELERATORS; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 59 BASIC BIOLOGICAL SCIENCES; ANIMALS; ATOMS; BIOLOGY; CATALYSTS; CHEMISTRY; CONVERGENCE; ENZYMES; FERMILAB ACCELERATOR; GENETICS; MACHINERY; PHYSICS; PROTEINS; STANFORD LINEAR ACCELERATOR CENTER; SYNCHROTRON RADIATION; TRANSCRIPTION; SLAC; MOLECULAR MACHINES; PROTEIN CATALYSTS; RNA; TRANSCRIPTION MACHINERY; X-RAY BEAMS

Citation Formats

Kornberg, Roger. From Atoms to Animals: The Vital Force in Biology. United States: N. p., 2008. Web.
Kornberg, Roger. From Atoms to Animals: The Vital Force in Biology. United States.
Kornberg, Roger. Tue . "From Atoms to Animals: The Vital Force in Biology". United States. https://www.osti.gov/servlets/purl/1014052.
@article{osti_1014052,
title = {From Atoms to Animals: The Vital Force in Biology},
author = {Kornberg, Roger},
abstractNote = {Perhaps the most significant event in intellectual history has occurred over the past several decades, a convergence of the sciences, a blurring of the distinctions between disciplines, from physics to chemistry to biology. Fundamental questions about human existence have been answered in chemical terms. What brings matter to life? What are our origins? What is the basis of cognitive activity? These and related questions have been a fertile area for philosophy and nonscientific analysis. The long history of such alternative approaches persists to this day. Life chemistry is explained by protein catalysts, in their simplest form known as enzymes, and in their full complexity, referred to as molecular machines. An example of great significance is the so-called transcription machinery, which reads out the genetic code, to direct the formation and function of all living things. The atomic structure of the transcription machinery was determined at Stanford, with the use of intense X-ray beams and facilities at the Stanford Synchrotron Radiation Laboratory at SLAC. The result is an image of this complex machinery in action, bringing genetic information to life.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2008},
month = {2}
}

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