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Title: Self-Control in Cocaine Addiction (440th Brookhaven Lecture)

A drug-addicted person may set a goal to abstain from taking drugs, yet soon afterwards he or she will ignore all warnings or reprimands, take an excessive amount of a drug, and possibly go much farthmore »er, such as trade in a car, or another valuable possession, for a couple of cocaine hits. This disadvantageous decision-making and drug- seeking behavior may continue despite catastrophic personal consequences -- for example, loss of job, health, or family -- even when the drug is no longer perceived as pleasurable. A series of brain-mapping studies and neuropsychological tests conducted at BNL has shown that people addicted to cocaine have an impaired ability to process rewards and exercise control, in a way that is directly linked to changes in the responsiveness in their prefrontal cortex, a part of the brain essential for advantageously monitoring and controlling one's own behavior. Goldstein will describe her research in this field, which was designed to test a theoretical model postulating that drug-addicted individuals disproportionately attribute value to their drug of choice -- at the expense of other potentially but no-longer-rewarding stimuli and at the same time, experience decreased ability to inhibit their drug use.« less
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Title: Self-Control in Cocaine Addiction (440th Brookhaven Lecture)
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Publication Date: 2008-10-01
OSTI Identifier: 1005226
DOE Contract Number: AC02-98CH10886
Other Number(s): TRN: US201117%%496
Resource Type: Multimedia
Resource Relation: Conference: Brookhaven Lecture Series: 1960 - Present, Lecture presented at Brookhaven National Laboratory, Upton, New York (United States) on October 01, 2008
Research Org: BNL (Brookhaven National Laboratory (BNL), Upton, NY (United States))
Sponsoring Org: USDOE Office of Science (SC)
Subject: 59 BASIC BIOLOGICAL SCIENCES ; 99 GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE ; BNL ; BRAIN ; COCAINE ; DECISION MAKING ; MONITORING ; STIMULI ; DRUG ABUSE
Country of Publication: United States
Language: English
Run Time: 1:08:51
System Entry Date: 2016-01-27