Metagenomic insights into the taxonomy, function, and dysbiosis of prokaryotic communities in octocorals
Abstract
Background. In octocorals (Cnidaria Octocorallia), the functional relationship between host health and its symbiotic consortium has yet to be determined. Here, we employed comparative metagenomics to uncover the distinct functional and phylogenetic features of the microbiomes of healthy Eunicella gazella, Eunicella verrucosa, and Leptogorgia sarmentosa tissues, in contrast with the microbiomes found in seawater and sediments. We further explored how the octocoral microbiome shifts to a pathobiome state in E. gazella. Results. Multivariate analyses based on 16S rRNA genes, Clusters of Orthologous Groups of proteins (COGs), Protein families (Pfams), and secondary metabolite-biosynthetic gene clusters annotated from 20 Illumina-sequenced metagenomes each revealed separate clustering of the prokaryotic communities of healthy tissue samples of the three octocoral species from those of necrotic E. gazella tissue and surrounding environments. While the healthy octocoral microbiome was distinguished by so-far uncultivated Endozoicomonadaceae, Oceanospirillales, and Alteromonadales phylotypes in all host species, a pronounced increase of Flavobacteriaceae and Alphaproteobacteria, originating from seawater, was observed in necrotic E. gazella tissue. Increased abundances of eukaryotic-like proteins, exonucleases, restriction endonucleases, CRISPR/Cas proteins, and genes encoding for heat-shock proteins, inorganic ion transport, and iron storage distinguished the prokaryotic communities of healthy octocoral tissue regardless of the host species. An increase ofmore »
- Authors:
-
- Universidade de Lisboa, Lisbon (Portugal)
- Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, Baja California (Mexico)
- Helmholtz Centre for Environmental Research (UFZ), Leipzig (Germany)
- Universidade do Algarve, Faro (Portugal)
- USDOE Joint Genome Institute (JGI), Berkeley, CA (United States)
- Universidade de Lisboa, Lisbon (Portugal); Universidade do Algarve, Faro (Portugal); USDOE Joint Genome Institute (JGI), Berkeley, CA (United States)
- Publication Date:
- Research Org.:
- Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Biological and Environmental Research (BER)
- OSTI Identifier:
- 1826912
- Grant/Contract Number:
- AC02-05CH11231
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Microbiome
- Additional Journal Information:
- Journal Volume: 9; Journal Issue: 1; Journal ID: ISSN 2049-2618
- Publisher:
- BioMed Central
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; Host-microbe interactions; Symbiosis; Holobiont; Gorgonians; Eunicella; Leptogorgia; Secondary metabolism; Necrosis
Citation Formats
Keller-Costa, T., Lago-Lestón, A., Saraiva, J. P., Toscan, R., Silva, S. G., Gonçalves, J., Cox, C. J., Kyrpides, N., Nunes da Rocha, U., and Costa, R. Metagenomic insights into the taxonomy, function, and dysbiosis of prokaryotic communities in octocorals. United States: N. p., 2021.
Web. doi:10.1186/s40168-021-01031-y.
Keller-Costa, T., Lago-Lestón, A., Saraiva, J. P., Toscan, R., Silva, S. G., Gonçalves, J., Cox, C. J., Kyrpides, N., Nunes da Rocha, U., & Costa, R. Metagenomic insights into the taxonomy, function, and dysbiosis of prokaryotic communities in octocorals. United States. https://doi.org/10.1186/s40168-021-01031-y
Keller-Costa, T., Lago-Lestón, A., Saraiva, J. P., Toscan, R., Silva, S. G., Gonçalves, J., Cox, C. J., Kyrpides, N., Nunes da Rocha, U., and Costa, R. Thu .
"Metagenomic insights into the taxonomy, function, and dysbiosis of prokaryotic communities in octocorals". United States. https://doi.org/10.1186/s40168-021-01031-y. https://www.osti.gov/servlets/purl/1826912.
@article{osti_1826912,
title = {Metagenomic insights into the taxonomy, function, and dysbiosis of prokaryotic communities in octocorals},
author = {Keller-Costa, T. and Lago-Lestón, A. and Saraiva, J. P. and Toscan, R. and Silva, S. G. and Gonçalves, J. and Cox, C. J. and Kyrpides, N. and Nunes da Rocha, U. and Costa, R.},
abstractNote = {Background. In octocorals (Cnidaria Octocorallia), the functional relationship between host health and its symbiotic consortium has yet to be determined. Here, we employed comparative metagenomics to uncover the distinct functional and phylogenetic features of the microbiomes of healthy Eunicella gazella, Eunicella verrucosa, and Leptogorgia sarmentosa tissues, in contrast with the microbiomes found in seawater and sediments. We further explored how the octocoral microbiome shifts to a pathobiome state in E. gazella. Results. Multivariate analyses based on 16S rRNA genes, Clusters of Orthologous Groups of proteins (COGs), Protein families (Pfams), and secondary metabolite-biosynthetic gene clusters annotated from 20 Illumina-sequenced metagenomes each revealed separate clustering of the prokaryotic communities of healthy tissue samples of the three octocoral species from those of necrotic E. gazella tissue and surrounding environments. While the healthy octocoral microbiome was distinguished by so-far uncultivated Endozoicomonadaceae, Oceanospirillales, and Alteromonadales phylotypes in all host species, a pronounced increase of Flavobacteriaceae and Alphaproteobacteria, originating from seawater, was observed in necrotic E. gazella tissue. Increased abundances of eukaryotic-like proteins, exonucleases, restriction endonucleases, CRISPR/Cas proteins, and genes encoding for heat-shock proteins, inorganic ion transport, and iron storage distinguished the prokaryotic communities of healthy octocoral tissue regardless of the host species. An increase of arginase and nitric oxide reductase genes, observed in necrotic E. gazella tissues, suggests the existence of a mechanism for suppression of nitrite oxide production by which octocoral pathogens may overcome the host’s immune system. Conclusions. This is the first study to employ primer-less, shotgun metagenome sequencing to unveil the taxonomic, functional, and secondary metabolism features of prokaryotic communities in octocorals. Our analyses reveal that the octocoral microbiome is distinct from those of the environmental surroundings, is host genus (but not species) specific, and undergoes large, complex structural changes in the transition to the dysbiotic state. Host-symbiont recognition, abiotic-stress response, micronutrient acquisition, and an antiviral defense arsenal comprising multiple restriction endonucleases, CRISPR/Cas systems, and phage lysogenization regulators are signatures of prokaryotic communities in octocorals. We argue that these features collectively contribute to the stabilization of symbiosis in the octocoral holobiont and constitute beneficial traits that can guide future studies on coral reef conservation and microbiome therapy.},
doi = {10.1186/s40168-021-01031-y},
journal = {Microbiome},
number = 1,
volume = 9,
place = {United States},
year = {Thu Mar 25 00:00:00 EDT 2021},
month = {Thu Mar 25 00:00:00 EDT 2021}
}
Works referenced in this record:
Ankyrin-repeat proteins from sponge symbionts modulate amoebal phagocytosis
journal, August 2013
- Nguyen, Mary T. H. D.; Liu, Michael; Thomas, Torsten
- Molecular Ecology, Vol. 23, Issue 6
Minimum Information about a Biosynthetic Gene cluster
journal, August 2015
- Medema, Marnix H.; Kottmann, Renzo; Yilmaz, Pelin
- Nature Chemical Biology, Vol. 11, Issue 9
Associations between species and groups of sites: indices and statistical inference
journal, December 2009
- Cáceres, Miquel De; Legendre, Pierre
- Ecology, Vol. 90, Issue 12
Bacteriome Structure, Function, and Probiotics in Fish Larviculture: The Good, the Bad, and the Gaps
journal, February 2021
- Borges, Nuno; Keller-Costa, Tina; Sanches-Fernandes, Gracinda M. M.
- Annual Review of Animal Biosciences, Vol. 9, Issue 1
The standard operating procedure of the DOE-JGI Microbial Genome Annotation Pipeline (MGAP v.4)
journal, October 2015
- Huntemann, Marcel; Ivanova, Natalia N.; Mavromatis, Konstantinos
- Standards in Genomic Sciences, Vol. 10, Issue 1
Compositional homogeneity in the pathobiome of a new, slow-spreading coral disease
journal, November 2019
- Sweet, Michael; Burian, Alfred; Fifer, James
- Microbiome, Vol. 7, Issue 1
A framework for estimating niche metrics using the resemblance between qualitative resources
journal, April 2011
- De Cáceres, Miquel; Sol, Daniel; Lapiedra, Oriol
- Oikos, Vol. 120, Issue 9
Bacterial Communities of the Gorgonian Octocoral Pseudopterogorgia elisabethae
journal, August 2013
- Correa, Hebelin; Haltli, Brad; Duque, Carmenza
- Microbial Ecology, Vol. 66, Issue 4
On the Importance of the Microbiome and Pathobiome in Coral Health and Disease
journal, January 2017
- Sweet, Michael J.; Bulling, Mark T.
- Frontiers in Marine Science, Vol. 4
CRISPR-Cas Defense System and Potential Prophages in Cyanobacteria Associated with the Coral Black Band Disease
journal, December 2016
- Buerger, Patrick; Wood-Charlson, Elisha M.; Weynberg, Karen D.
- Frontiers in Microbiology, Vol. 7
Nitric oxide and cnidarian bleaching: an eviction notice mediates breakdown of a symbiosis
journal, July 2006
- Perez, Santiago; Weis, Virginia
- Journal of Experimental Biology, Vol. 209, Issue 14
Long-Term Temperature Stress in the Coral Model Aiptasia Supports the “Anna Karenina Principle” for Bacterial Microbiomes
journal, May 2019
- Ahmed, Hanin Ibrahim; Herrera, Marcela; Liew, Yi Jin
- Frontiers in Microbiology, Vol. 10
A catastrophic mass-mortality episode of gorgonians and other organisms in the Ligurian Sea (North-western Mediterranean), summer 1999
journal, July 2000
- Cerrano, C.; Bavestrello, G.; Bianchi, C. N.
- Ecology Letters, Vol. 3, Issue 4
The Draft Genome of an Octocoral, Dendronephthya gigantea
journal, March 2019
- Jeon, Yeonsu; Park, Seung Gu; Lee, Nayun
- Genome Biology and Evolution, Vol. 11, Issue 3
InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams
journal, May 2015
- Heberle, Henry; Meirelles, Gabriela Vaz; da Silva, Felipe R.
- BMC Bioinformatics, Vol. 16, Issue 1
Microbiota of Healthy Corals Are Active against Fungi in a Light-Dependent Manner
journal, August 2014
- Moree, Wilna J.; McConnell, Oliver J.; Nguyen, Don D.
- ACS Chemical Biology, Vol. 9, Issue 10
Bacteria of the genus Endozoicomonas dominate the microbiome of the Mediterranean gorgonian coral Eunicella cavolini
journal, April 2013
- Bayer, T.; Arif, C.; Ferrier-Pagès, C.
- Marine Ecology Progress Series, Vol. 479
Marine probiotics: increasing coral resistance to bleaching through microbiome manipulation
journal, December 2018
- Rosado, Phillipe M.; Leite, Deborah C. A.; Duarte, Gustavo A. S.
- The ISME Journal, Vol. 13, Issue 4
Expressing cytotoxic compounds in Escherichia coli Nissle 1917 for tumor-targeting therapy
journal, March 2019
- Li, Ruijuan; Helbig, Linda; Fu, Jun
- Research in Microbiology, Vol. 170, Issue 2
metaSPAdes: a new versatile metagenomic assembler
journal, March 2017
- Nurk, Sergey; Meleshko, Dmitry; Korobeynikov, Anton
- Genome Research, Vol. 27, Issue 5
Piggyback-the-Winner in host-associated microbial communities
journal, July 2016
- Silveira, Cynthia B.; Rohwer, Forest L.
- npj Biofilms and Microbiomes, Vol. 2, Issue 1
Metagenomic analysis of the microbial community associated with the coral Porites astreoides
journal, November 2007
- Wegley, Linda; Edwards, Robert; Rodriguez-Brito, Beltran
- Environmental Microbiology, Vol. 9, Issue 11
Transcriptome, expression, and activity analyses reveal a vital heat shock protein 70 in the stress response of stony coral Pocillopora damicornis
journal, February 2018
- Zhang, Yidan; Zhou, Zhi; Wang, Lingui
- Cell Stress and Chaperones, Vol. 23, Issue 4
EBI metagenomics in 2016 - an expanding and evolving resource for the analysis and archiving of metagenomic data
journal, November 2015
- Mitchell, Alex; Bucchini, Francois; Cochrane, Guy
- Nucleic Acids Research, Vol. 44, Issue D1
Marine natural products
journal, January 2016
- Blunt, John W.; Copp, Brent R.; Keyzers, Robert A.
- Natural Product Reports, Vol. 33, Issue 3
Culturing captures members of the soil rare biosphere: Rare biosphere of soil
journal, July 2012
- Shade, Ashley; Hogan, Clifford S.; Klimowicz, Amy K.
- Environmental Microbiology, Vol. 14, Issue 9
Ecological Shifts in Mediterranean Coralligenous Assemblages Related to Gorgonian Forest Loss
journal, July 2014
- Ponti, Massimo; Perlini, Rossella Angela; Ventra, Vincenzo
- PLoS ONE, Vol. 9, Issue 7
The DNA Exonucleases of Escherichia coli
journal, June 2011
- Lovett, Susan T.
- EcoSal Plus, Vol. 4, Issue 2
Bisucaberin B, a Linear Hydroxamate Class Siderophore from the Marine Bacterium Tenacibaculum mesophilum
journal, April 2013
- Fujita, Masaki; Nakano, Koji; Sakai, Ryuichi
- Molecules, Vol. 18, Issue 4
CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA
journal, December 2008
- Marraffini, Luciano A.; Sontheimer, Erik J.
- Science, Vol. 322, Issue 5909
MetaWRAP—a flexible pipeline for genome-resolved metagenomic data analysis
journal, September 2018
- Uritskiy, Gherman V.; DiRuggiero, Jocelyne; Taylor, James
- Microbiome, Vol. 6, Issue 1
Mass mortality hits gorgonian forests at Montecristo Island
journal, October 2018
- Turicchia, E.; Abbiati, M.; Sweet, M.
- Diseases of Aquatic Organisms, Vol. 131, Issue 1
Primary Isolation and Characterization of Tenacibaculum maritimum from Chilean Atlantic Salmon Mortalities Associated with a Pseudochattonella spp. Algal Bloom
journal, June 2017
- Apablaza, Patricia; Frisch, Kathleen; Brevik, Øyvind Jakobsen
- Journal of Aquatic Animal Health, Vol. 29, Issue 3
Coral-Associated Bacteria and Their Role in the Biogeochemical Cycling of Sulfur
journal, April 2009
- Raina, J. -B.; Tapiolas, D.; Willis, B. L.
- Applied and Environmental Microbiology, Vol. 75, Issue 11
Coral microbial community dynamics in response to anthropogenic impacts near a major city in the central Red Sea
journal, April 2016
- Ziegler, Maren; Roik, Anna; Porter, Adam
- Marine Pollution Bulletin, Vol. 105, Issue 2
The past, present, and future of coral heat stress studies
journal, August 2019
- Cziesielski, Maha J.; Schmidt‐Roach, Sebastian; Aranda, Manuel
- Ecology and Evolution, Vol. 9, Issue 17
Modulation of the Arginase Pathway in the Context of Microbial Pathogenesis: A Metabolic Enzyme Moonlighting as an Immune Modulator
journal, June 2010
- Das, Priyanka; Lahiri, Amit; Lahiri, Ayan
- PLoS Pathogens, Vol. 6, Issue 6
Coral microbiome dynamics, functions and design in a changing world
journal, July 2019
- van Oppen, Madeleine J. H.; Blackall, Linda L.
- Nature Reviews Microbiology, Vol. 17, Issue 9
Comparative genome analysis provides novel insight into the interaction of Aquimarina sp. AD1, BL5 and AD10 with their macroalgal host
journal, August 2019
- Hudson, Jennifer; Kumar, Vipra; Egan, Suhelen
- Marine Genomics, Vol. 46
MIBiG 2.0: a repository for biosynthetic gene clusters of known function
journal, October 2019
- Kautsar, Satria A.; Blin, Kai; Shaw, Simon
- Nucleic Acids Research
Lytic to temperate switching of viral communities
journal, March 2016
- Knowles, B.; Silveira, C. B.; Bailey, B. A.
- Nature, Vol. 531, Issue 7595
Disturbance to conserved bacterial communities in the cold-water gorgonian coral Eunicella verrucosa
journal, August 2014
- Ransome, Emma; Rowley, Sonia J.; Thomas, Simon
- FEMS Microbiology Ecology
Stress and stability: applying the Anna Karenina principle to animal microbiomes
journal, August 2017
- Zaneveld, Jesse R.; McMinds, Ryan; Vega Thurber, Rebecca
- Nature Microbiology, Vol. 2, Issue 9
Transient Shifts in Bacterial Communities Associated with the Temperate Gorgonian Paramuricea clavata in the Northwestern Mediterranean Sea
journal, February 2013
- La Rivière, Marie; Roumagnac, Marie; Garrabou, Joaquim
- PLoS ONE, Vol. 8, Issue 2
Responses of Coral-Associated Bacterial Communities to Local and Global Stressors
journal, August 2017
- McDevitt-Irwin, Jamie M.; Baum, Julia K.; Garren, Melissa
- Frontiers in Marine Science, Vol. 4
The Assimilation of Diazotroph-Derived Nitrogen by Scleractinian Corals Depends on Their Metabolic Status
journal, March 2017
- Bednarz, Vanessa N.; Grover, Renaud; Maguer, Jean-François
- mBio, Vol. 8, Issue 1
Microbial functional structure of Montastraea faveolata , an important Caribbean reef-building coral, differs between healthy and yellow-band diseased colonies
journal, February 2010
- Kimes, Nikole E.; Van Nostrand, Joy D.; Weil, Ernesto
- Environmental Microbiology, Vol. 12, Issue 2
Paenibacterin, a novel broad-spectrum lipopeptide antibiotic, neutralises endotoxins and promotes survival in a murine model of Pseudomonas aeruginosa-induced sepsis
journal, July 2014
- Huang, En; Yousef, Ahmed E.
- International Journal of Antimicrobial Agents, Vol. 44, Issue 1
Pseudoalteromonas phenolica sp. nov., a novel marine bacterium that produces phenolic anti-methicillin-resistant Staphylococcus aureus substances
journal, March 2003
- Isnansetyo, Alim; Kamei, Yuto
- International Journal of Systematic and Evolutionary Microbiology, Vol. 53, Issue 2
Accelerated Profile HMM Searches
journal, October 2011
- Eddy, Sean R.
- PLoS Computational Biology, Vol. 7, Issue 10
Evidence for host specificity among dominant bacterial symbionts in temperate gorgonian corals
journal, August 2015
- La Rivière, Marie; Garrabou, Joaquim; Bally, Marc
- Coral Reefs, Vol. 34, Issue 4
Diseases affect cold-water corals too: Eunicella verrucosa (Cnidaria: Gorgonacea) necrosis in SW England
journal, June 2007
- Hall-Spencer, Jm; Pike, J.; Munn, Cb
- Diseases of Aquatic Organisms, Vol. 76
Effects of sample handling and cultivation bias on the specificity of bacterial communities in keratose marine sponges
journal, November 2014
- Hardoim, Cristiane C. P.; Cardinale, Massimiliano; Cúcio, Ana C. B.
- Frontiers in Microbiology, Vol. 5
Characterization of heat-shock response of the marine bacterium Vibrio harveyi
journal, May 1995
- Klein, Gracjana; Walczak, Robert; Krasnowska, Ewa
- Molecular Microbiology, Vol. 16, Issue 4
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
journal, November 2003
- Shannon, P.
- Genome Research, Vol. 13, Issue 11
Host-microbe interactions in octocoral holobionts - recent advances and perspectives
journal, April 2018
- van de Water, Jeroen A. J. M.; Allemand, Denis; Ferrier-Pagès, Christine
- Microbiome, Vol. 6, Issue 1
Comparative Assessment of Mediterranean Gorgonian-Associated Microbial Communities Reveals Conserved Core and Locally Variant Bacteria
journal, October 2016
- van de Water, Jeroen A. J. M.; Melkonian, Rémy; Voolstra, Christian R.
- Microbial Ecology, Vol. 73, Issue 2
Microbes in the coral holobiont: partners through evolution, development, and ecological interactions
journal, January 2015
- Thompson, Janelle R.; Rivera, Hanny E.; Closek, Collin J.
- Frontiers in Cellular and Infection Microbiology, Vol. 4
16SrDNA Pyrosequencing of the Mediterranean Gorgonian Paramuricea clavata Reveals a Link among Alterations in Bacterial Holobiont Members, Anthropogenic Influence and Disease Outbreaks
journal, June 2013
- Vezzulli, Luigi; Pezzati, Elisabetta; Huete-Stauffer, Carla
- PLoS ONE, Vol. 8, Issue 6
A multifaceted role for polyamines in bacterial pathogens
journal, April 2008
- Shah, Pratik; Swiatlo, Edwin
- Molecular Microbiology, Vol. 68, Issue 1
The gorgonian coral Eunicella labiata hosts a distinct prokaryotic consortium amenable to cultivation
journal, October 2017
- Keller-Costa, Tina; Eriksson, Dominic; Gonçalves, Jorge M. S.
- FEMS Microbiology Ecology, Vol. 93, Issue 12
antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline
journal, April 2019
- Blin, Kai; Shaw, Simon; Steinke, Katharina
- Nucleic Acids Research, Vol. 47, Issue W1
Spatial and depth-associated distribution patterns of shallow gorgonians in the Algarve coast (Portugal, NE Atlantic)
journal, December 2012
- Cúrdia, João; Monteiro, Pedro; Afonso, Carlos M. L.
- Helgoland Marine Research, Vol. 67, Issue 3
Genomic blueprints of sponge-prokaryote symbiosis are shared by low abundant and cultivatable Alphaproteobacteria
journal, February 2019
- Karimi, Elham; Keller-Costa, Tina; Slaby, Beate M.
- Scientific Reports, Vol. 9, Issue 1
Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters
journal, July 2014
- Cimermancic, Peter; Medema, Marnix H.; Claesen, Jan
- Cell, Vol. 158, Issue 2
Isolation and activity of Xenorhabdus antimicrobial compounds against the plant pathogens Erwinia amylovora and Phytophthora nicotianae
journal, September 2009
- Böszörményi, E.; Érsek, T.; Fodor, A.
- Journal of Applied Microbiology, Vol. 107, Issue 3
Discovery of recombinases enables genome mining of cryptic biosynthetic gene clusters in Burkholderiales species
journal, April 2018
- Wang, Xue; Zhou, Haibo; Chen, Hanna
- Proceedings of the National Academy of Sciences, Vol. 115, Issue 18
Bioactive Secondary Metabolites from Octocoral-Associated Microbes—New Chances for Blue Growth
journal, December 2018
- Raimundo, Inês; Silva, Sandra; Costa, Rodrigo
- Marine Drugs, Vol. 16, Issue 12
IMG/M v.5.0: an integrated data management and comparative analysis system for microbial genomes and microbiomes
journal, October 2018
- Chen, I-Min A.; Chu, Ken; Palaniappan, Krishna
- Nucleic Acids Research, Vol. 47, Issue D1
Genome-reconstruction for eukaryotes from complex natural microbial communities
journal, March 2018
- West, Patrick T.; Probst, Alexander J.; Grigoriev, Igor V.
- Genome Research, Vol. 28, Issue 4
A genomic view of the reef-building coral Porites lutea and its microbial symbionts
journal, September 2019
- Robbins, Steven J.; Singleton, Caitlin M.; Chan, Cheong Xin
- Nature Microbiology, Vol. 4, Issue 12
Insights into the Coral Microbiome: Underpinning the Health and Resilience of Reef Ecosystems
journal, September 2016
- Bourne, David G.; Morrow, Kathleen M.; Webster, Nicole S.
- Annual Review of Microbiology, Vol. 70, Issue 1
The nature of plant growth-promoting effects of a pseudoalteromonad associated with the marine algae Laminaria japonica and linked to catalase excretion
journal, May 2006
- Dimitrieva, G. Y.; Crawford, R. L.; Yuksel, G. U.
- Journal of Applied Microbiology, Vol. 100, Issue 5
Identification of Candidate Coral Pathogens on White Band Disease-Infected Staghorn Coral
journal, August 2015
- Gignoux-Wolfsohn, Sarah A.; Vollmer, Steven V.
- PLOS ONE, Vol. 10, Issue 8
A member of the Roseobacter clade, Octadecabacter sp., is the dominant symbiont in the brittle star Amphipholis squamata
journal, February 2018
- Morrow, Kathleen M.; Tedford, Abbey Rose; Pankey, M. Sabrina
- FEMS Microbiology Ecology, Vol. 94, Issue 4
Vibrio infections triggering mass mortality events in a warming Mediterranean Sea: Vibrio infections triggering sea-fan mass mortality
journal, March 2010
- Vezzulli, Luigi; Previati, Monica; Pruzzo, Carla
- Environmental Microbiology, Vol. 12, Issue 7
Temporal dynamics of prokaryotic communities in the marine sponge Sarcotragus spinosulus
journal, June 2014
- Hardoim, Cristiane C. P.; Costa, Rodrigo
- Molecular Ecology, Vol. 23, Issue 12
Type III Secretion System of Beneficial Rhizobacteria Pseudomonas simiae WCS417 and Pseudomonas defensor WCS374
journal, July 2019
- Stringlis, Ioannis A.; Zamioudis, Christos; Berendsen, Roeland L.
- Frontiers in Microbiology, Vol. 10
Differential specificity between closely related corals and abundant Endozoicomonas endosymbionts across global scales
journal, July 2016
- Neave, Matthew J.; Rachmawati, Rita; Xun, Liping
- The ISME Journal, Vol. 11, Issue 1
Spirochaetes dominate the microbial community associated with the red coral Corallium rubrum on a broad geographic scale
journal, June 2016
- van de Water, Jeroen A. J. M.; Melkonian, Rémy; Junca, Howard
- Scientific Reports, Vol. 6, Issue 1
Antibacterial Activity of Pseudoalteromonas in the Coral Holobiont
journal, July 2012
- Shnit-Orland, Maya; Sivan, Alex; Kushmaro, Ariel
- Microbial Ecology, Vol. 64, Issue 4
Functional genomic signatures of sponge bacteria reveal unique and shared features of symbiosis
journal, June 2010
- Thomas, Torsten; Rusch, Doug; DeMaere, Matt Z.
- The ISME Journal, Vol. 4, Issue 12